(4S)-4-Phenyl-1,3-thiazolidine-2-thione

Basic Information

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CAS Number

185137-29-5

Molecular Formula

C9H9NS2

Molecular Weight

195.31 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

127.0 to 131.0 deg-C

Boiling Point

322.2°C at 760 mmHg

SMILES

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C1C(NC(=S)S1)C2=CC=CC=C2

InChI

InChI=1S/C9H9NS2/c11-9-10-8(6-12-9)7-4-2-1-3-5-7/h1-5,8H,6H2,(H,10,11)/t8-/m1/s1

InChIKey

IEXSISKCCADMLK-MRVPVSSYSA-N

LogP

2.349

Topological Polar Surface Area

12.03 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

175

Safety Information

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Hazard Statement

Synonyms & References

English

CS-0093691
DTXSID20462621
(S)-4-Phenylthiazolidine-2-thione
AKOS006344722
(4S)-4-phenyl-1,3-thiazolidine-2-thione
J-011868
SCHEMBL5993375
(S)-4-Phenyl-1,3-thiazolidine-2-thione
(R)-(-)-4-Phenyl-1,3-thiazolidine-2-thione
A926659
S-4-Phenyl-1,3-thiazolidine-2-thione
IEXSISKCCADMLK-MRVPVSSYSA-N
T71985
AS-63571
P1960
MFCD06658214
AMY14572
185137-29-5
(S)-(+)-4-Phenyl-1,3-thiazolidine-2-thione
4(S)-phenyl-thiazolidine-2-thione
2-Thiazolidinethione, 4-phenyl-, (4S)-
2-Thiazolidinethione,4-phenyl-, (4S)-
(S)-4-phenylthiazolidinethione
39911_FLUKA
4-phenylthiazolidine-2-thione
4-phenylthiazolidinethione
ACT02351
ANW-73062
CTK4D8931
(S)-(+)-4-PHENYL-1,3-THIAZOLIDINE-2-THIONE
4beta-Phenylthiazolidine-2-thione

MDL Number

MFCD06658214

FAQ

What are the physical and chemical properties of (4S)-4-Phenyl-1,3-thiazolidine-2-thione (CAS: 185137-29-5)?

(4S)-4-Phenyl-1,3-thiazolidine-2-thione is a white crystalline solid with a molecular weight of 192.22 g/mol. It is soluble in organic solvents like DMSO and DMF. This compound is characterized by its low solubility in water. It exhibits good reactivity, particularly towards nucleophiles, making it suitable for various synthetic transformations. It is stable under normal conditions but should be protected from moisture and air to prevent hydrolysis.

How is (4S)-4-Phenyl-1,3-thiazolidine-2-thione (CAS: 185137-29-5) typically synthesized?

(4S)-4-Phenyl-1,3-thiazolidine-2-thione can be synthesized by the condensation of 4-phenylthiazolidine-2-thione with appropriate reagents under basic conditions. Commonly, this involves the use of sodium hydride as a base in a suitable solvent such as dimethylformamide (DMF). The reaction is typically carried out at room temperature, yielding a high selectivity and good yield. The exact method may vary depending on the starting materials and desired purity of the product.

What industries use (4S)-4-Phenyl-1,3-thiazolidine-2-thione (CAS: 185137-29-5)?

(4S)-4-Phenyl-1,3-thiazolidine-2-thione finds applications in pharmaceuticals, particularly in the development of bioactive compounds and drugs targeting specific biological pathways. It is also used in the synthesis of polymers, where it acts as a functional monomer. Additionally, it is employed in the manufacturing of sensors for detecting various gases and in the production of semiconductors for their specific chemical and electronic properties.

What precautions should be taken when handling (4S)-4-Phenyl-1,3-thiazolidine-2-thione (CAS: 185137-29-5)?

When handling (4S)-4-Phenyl-1,3-thiazolidine-2-thione, it is crucial to wear appropriate personal protective equipment (PPE) including gloves, safety glasses, and a lab coat. This compound should be used in a well-ventilated area or a fume hood to minimize exposure to airborne particles. It is important to follow standard laboratory safety protocols and keep an up-to-date safety data sheet (SDS) on hand. Spills should be cleaned up immediately using appropriate absorbents and disposed of according to local regulations.