1,3-Bis(trimethylsilyl)urea

Basic Information

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CAS Number

18297-63-7

Molecular Formula

C7H20N2OSi2

Molecular Weight

204.42 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Physical Properties

Melting Point

219-221 °C

Boiling Point

222°C

Water Solubility

Reacts with water.

Flash Point

65°C

Solubility

pyridine: soluble100mg/mL, clear to slightly hazy, colorless to light yellow

SMILES

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C[Si](C)(C)NC(=O)N[Si](C)(C)C

InChI

InChI=1S/C7H20N2OSi2/c1-11(2,3)8-7(10)9-12(4,5)6/h1-6H3,(H2,8,9,10)

InChIKey

MASDFXZJIDNRTR-UHFFFAOYSA-N

LogP

1.9553999999999998

Topological Polar Surface Area

41.13 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

151

Safety Information

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GHS Hazard Pictograms

H228

Hazard Statement

H228 Flammable solid
Flammable solids

Sensitiveness

Moisture Sensitive

Synonyms & References

English

N,N'-bis-(trimethylsilyl)-urea
Nn'-Bis(Trimethylsilyl)Urea
bis-(trimethylsilyl-)urea
BP-21121
FT-0629428
N,N'-Bis(trimethylsilyl)urea
NS00051878
18297-63-7
EN300-25973
1,3-Bis(trimethylsilyl)urea (BSU)
bis (trimethylsilyl) urea
Urea, N,N'-bis(trimethylsilyl)-
Bis(trimethylsilyl) derivative of Urea
N,N'-Di(trimethylsilyl)urea
N,N'-Bis(trimethylsilyl)urea, purum, >=98.0% (N)
1,3-Bis(trimethylsilyl)urea
N,N'-bis-trimethylsilylurea
DTXSID7066358
127290-39-5
1,3-Bis(trimethylsilyl)urea.
SCHEMBL607546
Urea, bis-TMS
MFCD00008260
EINECS 242-177-9
AKOS000121142
S02850
1,3-Bis(trimethylsilyl)urea, 95%
Urea, 1,3-bis(trimethylsilyl)-
bis-(trimethylsilyl)urea
N,N'-bis-trimethylsilyl urea
N1,N2-Bis(trimethylsilyl)urea

MDL Number

MFCD00008260

Customs Code

29310095

FAQ

What are the physical and chemical properties of 1,3-Bis(trimethylsilyl)urea (CAS: 18297-63-7)?

1,3-Bis(trimethylsilyl)urea (CAS: 18297-63-7) is a colorless crystalline solid with a molecular weight of approximately 254.41 g/mol. It has a high solubility in organic solvents such as acetone and dimethylformamide. Chemically, it is stable under normal conditions but can react with strong acids and bases. It is often used in organic synthesis and as a protective group reagent.

How is 1,3-Bis(trimethylsilyl)urea (CAS: 18297-63-7) typically synthesized?

1,3-Bis(trimethylsilyl)urea is typically synthesized via the reaction of isocyanuric acid with trimethylsilyl chloride. The synthesis involves the formation of an intermediate silyl isocyanate followed by its reaction with itself to give 1,3-Bis(trimethylsilyl)urea. This reaction is catalyzed by strong acids and proceeds with good yield and selectivity.

What industries use 1,3-Bis(trimethylsilyl)urea (CAS: 18297-63-7)?

1,3-Bis(trimethylsilyl)urea (CAS: 18297-63-7) is primarily used in the pharmaceuticals and organic synthesis industries. It serves as a protecting group in synthetic chemistry, particularly in the modification of amine functionalities. It is also used in the production of semiconductors and some polymer applications due to its ability to control reactivity and molecular structure.

What precautions should be taken when handling 1,3-Bis(trimethylsilyl)urea (CAS: 18297-63-7)?

When handling 1,3-Bis(trimethylsilyl)urea (CAS: 18297-63-7), it is important to use proper personal protective equipment (PPE) such as gloves and safety goggles. Operations should be conducted in a well-ventilated area or fume hood. Spills should be cleaned up carefully using appropriate absorbent materials. Storage should be in a cool, dry place away from acids and bases. Always consult a Material Safety Data Sheet (MSDS) for detailed handling and safety information.