6-Amino-5-bromonicotinic acid

Basic Information

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CAS Number

180340-69-6

Molecular Formula

C6H5BrN2O2

Molecular Weight

217.02 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

378℃ at 760 mmHg

Density

1.91

Flash Point

378.001 °C at 760 mmHg

Refractive Index

1.685

SMILES

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C1=C(C=NC(=C1Br)N)C(=O)O

InChI

InChI=1S/C6H5BrN2O2/c7-4-1-3(6(10)11)2-9-5(4)8/h1-2H,(H2,8,9)(H,10,11)

InChIKey

UOUDHTBHPQJUPS-UHFFFAOYSA-N

LogP

1.1245

Topological Polar Surface Area

76.21 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

165

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

6-amino-5-bromopyridine-3-carboxylic acid
6-amino-5-bromo-pyridine-3-carboxylic acid
6-Amino-5-bromo-nicotinic acid
AKOS005064134
FT-0645940
AU-004/43508218
SY009598
EN300-109680
SCHEMBL186549
J-518239
3-Pyridinecarboxylic acid, 6-amino-5-bromo-
MFCD11109515
HA-0859
A3996
BCP27531
6-Amino-5-bromonicotinic acid, AldrichCPR
6-AMINO-5-BROMONICOTINIC ACID
CS-10495
UOUDHTBHPQJUPS-UHFFFAOYSA-N
AM20050891
6-Amino-5-bromonicotinicacid
CS-W022442
180340-69-6
Z1269112095
SB10479
DTXSID30627981
3-Pyridinecarboxylic acid, 6-amino-5-bromo
6-Amino-5-bromonicotinic acid
6-Amino-5-bromopyridin-3-carboxylic acid
2-AMino-3-broMo-5-pyridinecarboxylic acid
KSC169I1P

MDL Number

MFCD11109515

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 6-Amino-5-bromonicotinic acid (CAS: 180340-69-6)?

6-Amino-5-bromonicotinic acid is a white crystalline solid with a molecular weight of approximately 241.03 g/mol. It is slightly soluble in water and ethanol. Chemically, it is less reactive than its parent compound, nicotinic acid, due to the presence of the amino group and bromine substituent.

How is 6-Amino-5-bromonicotinic acid (CAS: 180340-69-6) typically synthesized?

6-Amino-5-bromonicotinic acid is typically synthesized by bromination of 6-aminonicotinic acid. This involves the reaction of 6-aminonicotinic acid with bromine in the presence of a base like sodium hydroxide. The reaction is conducted in a polar aprotic solvent such as acetonitrile.

What industries use 6-Amino-5-bromonicotinic acid (CAS: 180340-69-6)?

6-Amino-5-bromonicotinic acid is used primarily in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the organic synthesis field, where it is used as an intermediate for the preparation of various compounds.

What precautions should be taken when handling 6-Amino-5-bromonicotinic acid (CAS: 180340-69-6)?

When handling 6-Amino-5-bromonicotinic acid, it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Work should be conducted in a well-ventilated area or a fume hood. Store the compound in a cool, dry place away from direct sunlight and flammable materials. In case of spillage, neutralize the spill with an appropriate acid-base neutralizer and clean up according to standard laboratory safety procedures.