5-Carboxy Rhodamine-6G | CAS No. 180144-69-8

5-Carboxy Rhodamine-6G

Basic Information

CAS Number

180144-69-8

Molecular Formula

C27H27ClN2O5

Molecular Weight

494.97 g/mol

AD

Basic Physical Properties

CCNC1=CC2=C(C=C1C)C(=C3C=C(C(=[NH+]CC)C=C3O2)C)C4=C(C=C(C=C4)C(=O)O)C(=O)O.[Cl-]

InChI

InChI=1S/C27H26N2O5.ClH/c1-5-28-21-12-23-19(9-14(21)3)25(17-8-7-16(26(30)31)11-18(17)27(32)33)20-10-15(4)22(29-6-2)13-24(20)34-23;/h7-13,28H,5-6H2,1-4H3,(H,30,31)(H,32,33);1H

InChIKey

VSYBZFNXXNHSAG-UHFFFAOYSA-N

LogP

6.02420

Complexity

916

Synonyms & References

English

  • [9-(2,4-dicarboxyphenyl)-6-(ethylamino)-2,7-dimethylxanthen-3-ylidene]-ethylazanium,chloride
  • 5-Carboxyrhodamine 6G, single isomer
  • 9-(2,4-Dicarboxyphenyl)-3,6-bis(ethylaMino)-2,7-diMethylxanthyliuM Chloride
  • 5-Carboxy Rhodamine-6G
  • 180144-69-8
  • (3E)-9-(2,4-Dicarboxyphenyl)-N-ethyl-6-(ethylamino)-2,7-dimethyl-3H-xanthen-3-iminium chloride
  • 9-(2,4-Dicarboxyphenyl)-3,6-bis(ethylamino)-2,7-dimethylxanthylium Chloride
  • [9-(2,4-dicarboxyphenyl)-6-(ethylamino)-2,7-dimethylxanthen-3-ylidene]-ethylazanium;chloride
  • DTXSID80747300
  • 5-Carboxy rhodamine 6G
  • 5-Carboxyrhodamine 6G
  • Xanthylium, 9-(2,4-dicarboxyphenyl)-3,6-bis(ethylamino)-2,7-dimethyl-, chloride (1:1)

MDL Number

MFCD31563095

FAQ

What regulatory guidelines apply to 5-Carboxy Rhodamine-6G (CAS: 180144-69-8)?

5-Carboxy Rhodamine-6G (CAS: 180144-69-8) is classified under the Globally Harmonized System (GHS) as a category 4 carcinogen. It falls under the scope of REACH regulations in the European Union, requiring manufacturers and importers to register the substance if the tonnage threshold is exceeded. In the United States, it is subject to regulations by the U.S. Environmental Protection Agency (EPA) under the Toxic Substances Control Act (TSCA). Additionally, the FDA regulates its use in medical applications.

Are there alternatives to 5-Carboxy Rhodamine-6G (CAS: 180144-69-8) in synthesis?

5-Carboxy Rhodamine-6G (CAS: 180144-69-8) can be synthesized as an alternative to other fluorescent dyes such as Rhodamine B or Texas Red. Common alternative reagents include succinic anhydride for carboxylation. Other substituted derivatives like 5-(4-Carboxyphenyl)Rhodamine-6G can also serve as effective alternatives, depending on the specific application.

What is the market or research trend for 5-Carboxy Rhodamine-6G (CAS: 180144-69-8)?

The market for 5-Carboxy Rhodamine-6G (CAS: 180144-69-8) has seen steady growth, driven by its increasing use in life sciences research, particularly in fluorescence microscopy and flow cytometry. Research trends are shifting towards more sensitive and specific labeling techniques, which may lead to the development of new functional derivatives. The compound's stability and fluorescence make it a preferred choice for long-term cell imaging applications.

How should waste containing 5-Carboxy Rhodamine-6G (CAS: 180144-69-8) be handled?

Waste containing 5-Carboxy Rhodamine-6G (CAS: 180144-69-8) should be collected in appropriate containers and stored in a secure location away from ignition sources. The waste should be treated as a hazardous substance and disposed of via incineration or through professional chemical waste disposal services. Environmental protection measures include ensuring proper ventilation and using personal protective equipment during handling. Under the U.S. EPA's hazardous waste rules, it may also need to be classified and managed according to specific guidelines.

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