1-[4-(Methylamino)phenyl]ethanone

Basic Information

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CAS Number

17687-47-7

Molecular Formula

C9H11NO

Molecular Weight

149.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

103-107 °C

Boiling Point

281.7±23.0 ºC (760 Torr),

Flash Point

125.8±22.8 ºC,

SMILES

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CC(=O)C1=CC=C(C=C1)NC

InChI

InChI=1S/C9H11NO/c1-7(11)8-3-5-9(10-2)6-4-8/h3-6,10H,1-2H3

InChIKey

GDBAYICEBDZUNM-UHFFFAOYSA-N

LogP

1.9308999999999998

Topological Polar Surface Area

29.1 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

137

Safety Information

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GHS Hazard Pictograms

H317

Hazard Statement

H317 May cause an allergic skin reaction
Sensitization, Skin

Synonyms & References

English

DTXSID50469340
MFCD09261160
DS-8279
M2958
N12151
A881496
J-011238
Ethanone, 1-[4-(methylamino)phenyl]-
SY102187
Z1082871512
4-Acetyl-N-methylaniline, 97%
4 inverted exclamation mark -(Methylamino)acetophenone
1-(4-(Methylamino)phenyl)ethanone
SCHEMBL912761
AMY5226
CS-0155091
1-(4-methylamino-phenyl)-ethanone
4-Acetyl-N-methylaniline
4-N-Methylaminoacetophenone
F1791-1730
4'-(Methylamino)acetophenone
1-[4-(methylamino)phenyl]ethan-1-one
FT-0699647
Ethanone, 1-[4-(methylamino)phenyl]- (9CI)
17687-47-7
4-acetyl-n-methyl aniline
1-[4-(METHYLAMINO)PHENYL]ETHANONE
AKOS012391681
EN300-365696
1-[4-(methylamino)phenyl]ethanone
Ethanone,1-[4-(methylamino)phenyl]-

MDL Number

MFCD09261160

Customs Code

2922399090

FAQ

What are the physical and chemical properties of 1-[4-(Methylamino)phenyl]ethanone (CAS: 17687-47-7)?

1-[4-(Methylamino)phenyl]ethanone (CAS: 17687-47-7) is a white crystalline solid with a molecular weight of approximately 194.27 g/mol. It is soluble in organic solvents such as ethanol and acetone. This compound is chemically stable but can react with strong acids to form the corresponding N-methylated products. It is also known for its reactivity towards nucleophiles and electrophiles, making it a versatile reagent in organic synthesis.

How is 1-[4-(Methylamino)phenyl]ethanone (CAS: 17687-47-7) typically synthesized?

1-[4-(Methylamino)phenyl]ethanone can be synthesized via a reaction between 4-aminophenylacetic acid and methyl iodide in the presence of a base such as potassium carbonate. This synthesis yields a high yield of the desired product. The reaction is typically carried out in an aprotic solvent like dimethylformamide (DMF) under mild conditions, ensuring good selectivity and yield.

What industries use 1-[4-(Methylamino)phenyl]ethanone (CAS: 17687-47-7)?

1-[4-(Methylamino)phenyl]ethanone (CAS: 17687-47-7) is widely used in the pharmaceutical industry for the synthesis of various drug candidates due to its functional groups that can be easily modified. It is also utilized in the polymer industry for the development of novel materials. Additionally, it finds applications in sensor technology and semiconductor manufacturing due to its electronic properties.

What precautions should be taken when handling 1-[4-(Methylamino)phenyl]ethanone (CAS: 17687-47-7)?

When handling 1-[4-(Methylamino)phenyl]ethanone (CAS: 17687-47-7), it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a laboratory coat. This compound should be used in a well-ventilated area or a fume hood to avoid inhalation of fumes. Spills should be cleaned up immediately using appropriate absorbents, and the area should be thoroughly washed down. Always consult the safety data sheet (SDS) for detailed handling and disposal instructions.