1-[4-(Methylamino)phenyl]ethanone(CAS: 17687-47-7)

1-[4-(Methylamino)phenyl]ethanone (CAS: 17687-47-7) is a white crystalline solid with a molecular weight of approximately 194.27 g/mol. It is soluble in organic solvents such as ethanol and acetone. This compound is chemically stable but can react with strong acids to form the corresponding N-methylated products. It is also known for its reactivity towards nucleophiles and electrophiles, making it a versatile reagent in organic synthesis.

1-[4-(Methylamino)phenyl]ethanone can be synthesized via a reaction between 4-aminophenylacetic acid and methyl iodide in the presence of a base such as potassium carbonate. This synthesis yields a high yield of the desired product. The reaction is typically carried out in an aprotic solvent like dimethylformamide (DMF) under mild conditions, ensuring good selectivity and yield.

1-[4-(Methylamino)phenyl]ethanone (CAS: 17687-47-7) is widely used in the pharmaceutical industry for the synthesis of various drug candidates due to its functional groups that can be easily modified. It is also utilized in the polymer industry for the development of novel materials. Additionally, it finds applications in sensor technology and semiconductor manufacturing due to its electronic properties.

When handling 1-[4-(Methylamino)phenyl]ethanone (CAS: 17687-47-7), it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a laboratory coat. This compound should be used in a well-ventilated area or a fume hood to avoid inhalation of fumes. Spills should be cleaned up immediately using appropriate absorbents, and the area should be thoroughly washed down. Always consult the safety data sheet (SDS) for detailed handling and disposal instructions.