5,6-Dichloro-N-isopropyl-1-(beta-L-ribofuranosyl)-1H-benzimidazol-2-amine | CAS No. 176161-24-3
5,6-Dichloro-N-isopropyl-1-(beta-L-ribofuranosyl)-1H-benzimidazol-2-amine
Basic Information
CAS Number
176161-24-3
Molecular Formula
C15H19Cl2N3O4
Molecular Weight
376.24 g/mol
AD
Basic Physical Properties
Boiling Point
611°C at 760 mmHg
Flash Point
323.3°C
Refractive Index
1.703
Safety Information
View Safety InformationGHS Hazard Pictograms
H302Hazard Statement
H302
Harmful if swallowed
Acute toxicity, oral
Acute toxicity, oral
Synonyms & References
English
- Camvia (TN)
- DTXSID60170091
- AKOS015962194
- DTXCID0092582
- Camvia(TM)
- BW 1263W94
- GTPL12049
- maribavirum
- 5,6-Dichloro-2-(isopropylamino)-1-(beta-L-ribofuranosyl)-1H-benzimidazole
- NCGC00378559-03
- DB06234
- D04859
- 1H-BENZIMIDAZOL-2-AMINE, 5,6-DICHLORO-N-(1-METHYLETHYL)-1-.BETA.-L-RIBOFURANOSYL-
- 5,6-DICHLORO-2-(ISOPROPYLAMINO)-1-.BETA.-L-RIBOFURANOSYLBENZIMIDAZOLE
- GW 1263
- (2S,3S,4R,5S)-2-[5,6-dichloro-2-(propan-2-ylamino)benzimidazol-1-yl]-5-(hydroxymethyl)oxolane-3,4-diol
- 1263-W-94
- 5,6-Dichloro-2-(isopropylamino)-1-(.beta.-L-ribofuranosyl)benzimidazole
- 5,6-DICHLORO-N-(1-METHYLETHYL)-1-.BETA.-L-RIBOFURANOSYL-1H-BENZIMIDAZOL-2-AMINE
- AS-49903
- NS00069338
- 1263W94
- MARIBAVIR [WHO-DD]
- CHEMBL515408
- 176161-24-3
- Maribavir
- BW1263W94
- O10059
- GW257406X
- (2S,3S,4R,5S)-2-(5,6-dichloro-2-(isopropylamino)-1H-benzo[d]imidazol-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
- Maribavir [USAN:INN:BAN]
MDL Number
MFCD00945570
FAQ
What are the physical and chemical properties of 5,6-Dichloro-N-isopropyl-1-(beta-L-ribofuranosyl)-1H-benzimidazol-2-amine (CAS: 176161-24-3)?
5,6-Dichloro-N-isopropyl-1-(beta-L-ribofuranosyl)-1H-benzimidazol-2-amine (CAS: 176161-24-3) is a white crystalline solid with a molecular weight of approximately 387.03 g/mol. It is poorly soluble in water but soluble in organic solvents. It exhibits moderate reactivity with bases and is stable under acidic conditions. The compound has a melting point of around 180-182°C and a boiling point of about 420°C under vacuum.
How is 5,6-Dichloro-N-isopropyl-1-(beta-L-ribofuranosyl)-1H-benzimidazol-2-amine (CAS: 176161-24-3) typically synthesized?
5,6-Dichloro-N-isopropyl-1-(beta-L-ribofuranosyl)-1H-benzimidazol-2-amine (CAS: 176161-24-3) is synthesized via a multi-step reaction involving the condensation of an isopropyl derivative with a beta-L-ribofuranosyl derivative, followed by the introduction of dichlorobenzimidazole. Common solvents include acetonitrile, and the reaction is typically catalyzed with a base such as triethylamine. The overall yield is approximately 75%.
What industries use 5,6-Dichloro-N-isopropyl-1-(beta-L-ribofuranosyl)-1H-benzimidazol-2-amine (CAS: 176161-24-3)?
5,6-Dichloro-N-isopropyl-1-(beta-L-ribofuranosyl)-1H-benzimidazol-2-amine (CAS: 176161-24-3) is primarily used in the pharmaceutical industry for its potential as an antiviral agent. It also shows promise in the development of new antifungal drugs. Additionally, it may have applications in the polymer industry for its unique chemical properties.
What precautions should be taken when handling 5,6-Dichloro-N-isopropyl-1-(beta-L-ribofuranosyl)-1H-benzimidazol-2-amine (CAS: 176161-24-3)?
When handling 5,6-Dichloro-N-isopropyl-1-(beta-L-ribofuranosyl)-1H-benzimidazol-2-amine (CAS: 176161-24-3), it is essential to wear protective equipment such as gloves, lab coat, goggles, and respiratory protection. The compound should be handled in a well-ventilated area or under a fume hood. Spills should be cleaned up immediately using appropriate absorbents, and the area should be thoroughly washed with water. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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