Compound Q&A
How is 5,6-Dichloro-N-isopropyl-1-(beta-L-ribofuranosyl)-1H-benzimidazol-2-amine (CAS: 176161-24-3) typically synthesized?
Answer
5,6-Dichloro-N-isopropyl-1-(beta-L-ribofuranosyl)-1H-benzimidazol-2-amine (CAS: 176161-24-3) is synthesized via a multi-step reaction involving the condensation of an isopropyl derivative with a beta-L-ribofuranosyl derivative, followed by the introduction of dichlorobenzimidazole. Common solvents include acetonitrile, and the reaction is typically catalyzed with a base such as triethylamine. The overall yield is approximately 75%.
About
CAS No
176161-24-3
English Name
5,6-Dichloro-N-isopropyl-1-(beta-L-ribofuranosyl)-1H-benzimidazol-2-amine
Molecular Formula
C15H19Cl2N3O4
Molecular Weight
376.24 g/mol
SMILES
CC(C)NC1=NC2=CC(=C(C=C2N1C3C(C(C(O3)CO)O)O)Cl)Cl
InChIKey
KJFBVJALEQWJBS-XUXIUFHCSA-N
Last Updated: 2025-10-19 20:30