5-(Trifluoromethyl)-2-furaldehyde

Basic Information

View in Editor

CAS Number

17515-80-9

Molecular Formula

C6H3F3O2

Molecular Weight

164.08 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Aldehydes

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Boiling Point

184°Cat760mmHg

Density

1.397

Flash Point

65.1°C

Refractive Index

1.592

SMILES

View in Editor

C1=C(OC(=C1)C(F)(F)F)C=O

InChI

InChI=1S/C6H3F3O2/c7-6(8,9)5-2-1-4(3-10)11-5/h1-3H

InChIKey

KLVCIHFXPHKSPD-UHFFFAOYSA-N

LogP

2.1109

Topological Polar Surface Area

30.21 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

154

Safety Information

View Safety Information

Hazard Statement

Synonyms & References

English

AKOS006222941
Z1201620341
5-trifluoromethylfuran-2-carbaldehyde
SB61913
DTXSID00428785
MFCD00525585
5-trifluoromethyl-furan-2-carbaldehyde
17515-80-9
5-(trifluoromethyl)-2-furaldehyde, AldrichCPR
EN300-255109
5-(trifluoromethyl)furan-2-carbaldehyde
5-(Trifluoromethyl)-2-furaldehyde
SCHEMBL231078
5-(trifluoromethyl)-2-furancarboxaldehyde
FT-0637560
BP-10623
5-trifluoromethyl-2-furancarboxaldehyde
CS-D0416
4-Biphenylglyoxalhydrate
A811807
2-Furancarboxaldehyde, 5-(trifluoromethyl)-
5-(Trifluoromethyl)furan-2-carbaldehyde
2-Furancarboxaldehyde,5-(trifluoromethyl)-
2-Formyl-5-(trifluoromethyl)furan
5-(Trifluoromethyl)furfural
5-trifluoromethyl-2-furfural
5-trifluoromethylfurane-2-carboxaldehyde
5-(Trifluoromethyl)furan-2-carboxaldehyde, 2-Formyl-5-(trifluoromethyl)furan, 5-(Trifluoromethyl)furfural
5-(Trifluoromethyl)-2-furaldehyde97%
5-(Trifluoromethyl)-2-furaldehyde 97%

MDL Number

MFCD00525585

Customs Code

2932190090

FAQ

What are the physical and chemical properties of 5-(Trifluoromethyl)-2-furaldehyde (CAS: 17515-80-9)?

5-(Trifluoromethyl)-2-furaldehyde (CAS: 17515-80-9) is a colorless to light yellow liquid with a molecular weight of 177.07 g/mol. It has a high boiling point of 193-194°C and a density of 1.43 g/mL. It is slightly soluble in water but highly soluble in organic solvents. The compound is known for its high reactivity, particularly towards nucleophiles and reducing agents.

How is 5-(Trifluoromethyl)-2-furaldehyde (CAS: 17515-80-9) typically synthesized?

5-(Trifluoromethyl)-2-furaldehyde (CAS: 17515-80-9) is typically synthesized by the trifluoroacetylation of furfural using triflic anhydride as a catalyst. The reaction involves the formation of an intermediate triflate ester, which then undergoes nucleophilic attack to form the final aldehyde. The yield of the reaction can be up to 85%, and the product is usually obtained with high selectivity.

What industries use 5-(Trifluoromethyl)-2-furaldehyde (CAS: 17515-80-9)?

5-(Trifluoromethyl)-2-furaldehyde (CAS: 17515-80-9) is used in various industries, including pharmaceuticals for the synthesis of certain drugs, and as a precursor in the production of polymers and sensors. It is also utilized in the semiconductor industry for specific applications.

What precautions should be taken when handling 5-(Trifluoromethyl)-2-furaldehyde (CAS: 17515-80-9)?

When handling 5-(Trifluoromethyl)-2-furaldehyde (CAS: 17515-80-9), it is essential to use appropriate personal protective equipment (PPE), including gloves, safety goggles, and chemical-resistant clothing. Work should be carried out in a well-ventilated fume hood to minimize exposure. Spills should be cleaned up using suitable absorbents and disposed of according to local regulations. Always consult the safety data sheet (SDS) for detailed safety information.