(2,5-Difluorophenyl)hydrazine hydrochloride (1:1)

Basic Information

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CAS Number

175135-73-6

Molecular Formula

C6H7ClF2N2

Molecular Weight

180.59 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

210 ºC

Boiling Point

189.5°C at 760 mmHg

Flash Point

68.4°C

SMILES

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C1=CC(=C(C=C1F)NN)F.Cl

InChI

InChI=1S/C6H6F2N2.ClH/c7-4-1-2-5(8)6(3-4)10-9;/h1-3,10H,9H2;1H

InChIKey

LZKLZCSHMDRKJH-UHFFFAOYSA-N

LogP

1.6722

Topological Polar Surface Area

38.05 Å²

Hydrogen Bond Donor/Acceptor

3 / 2

Complexity

110

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(2,5-Difluorophenyl)hydrazinehydrochloride
2,5-difluorophenylhydrazine hydrochloride
LZKLZCSHMDRKJH-UHFFFAOYSA-N
EN300-7362033
AC-4206
FT-0610367
(2,5-difluorophenyl)hydrazine;hydrochloride
175135-73-6
(2,5-Difluoro-phenyl)-hydrazine hydrochloride
Hydrazine, (2,5-difluorophenyl)-, monohydrochloride
DTXSID20641010
(2,5-Difluorophenyl)hydrazine hydrochloride
AKOS015890157
SCHEMBL1408624
SY022155
DS-15387
(2,5-Difluorophenyl)hydrazine--hydrogen chloride (1/1)
1-(2,5-difluorophenyl)hydrazine hydrochloride
Hydrazine, (2,5-difluorophenyl)-, hydrochloride (1:1)
CS-W010750
2,5-difluorophenylhydrazine hcl
MFCD00013385
A811744
CK1205
2,5-Difluorophenylhydrazine, HCl
2,5-Difluorophenylhydrazine hydrochloride
2,5-Difluorophenylhydrazine HCl
Hydrazine,(2,5-difluorophenyl)-, monohydrochloride (9CI)
2,5-Difluorophenylhydrazine monohydrochloride
2,5-Difluorophenylhy
2,5-Difluorophenylhydrazine HCI

MDL Number

MFCD00013385

Customs Code

2928000090

FAQ

What are the physical and chemical properties of (2,5-Difluorophenyl)hydrazine hydrochloride (CAS: 175135-73-6)?

(2,5-Difluorophenyl)hydrazine hydrochloride is a solid crystalline compound with a molecular weight of approximately 208.94 g/mol. It has a pKa of 1.4 and is soluble in water and ethanol. This compound is known for its reactivity towards nucleophiles and its ability to form stable complexes with various metal ions. It is often used as a starting material in the synthesis of other organic compounds.

How is (2,5-Difluorophenyl)hydrazine hydrochloride (CAS: 175135-73-6) typically synthesized?

(2,5-Difluorophenyl)hydrazine hydrochloride is commonly synthesized by the reaction of 2,5-difluorophenyl hydrazine with hydrochloric acid in an appropriate solvent. The process is carried out in a fume hood under acidic conditions, and the yield is usually around 75-85%. The reaction is exothermic and requires careful control of temperature to prevent decomposition.

What industries use (2,5-Difluorophenyl)hydrazine hydrochloride (CAS: 175135-73-6)?

(2,5-Difluorophenyl)hydrazine hydrochloride is used in various industries. It is particularly important in pharmaceuticals, where it serves as a key intermediate in the synthesis of drugs. In addition, it is utilized in the polymer industry for the preparation of certain polymer additives. Its use in sensors and semiconductors is also growing due to its unique electronic properties.

What precautions should be taken when handling (2,5-Difluorophenyl)hydrazine hydrochloride (CAS: 175135-73-6)?

Handling (2,5-Difluorophenyl)hydrazine hydrochloride requires caution. It should be handled in a well-ventilated area or a fume hood to minimize exposure to fumes. Personal protective equipment (PPE) such as gloves, goggles, and safety goggles should be worn. Spills should be handled using appropriate absorbent materials and disposed of according to local regulations. It is important to always refer to the Safety Data Sheet (SDS) for detailed safety information.