Compound Q&A

How is (2,5-Difluorophenyl)hydrazine hydrochloride (CAS: 175135-73-6) typically synthesized?

Answer

(2,5-Difluorophenyl)hydrazine hydrochloride (1:1)
(2,5-Difluorophenyl)hydrazine hydrochloride is commonly synthesized by the reaction of 2,5-difluorophenyl hydrazine with hydrochloric acid in an appropriate solvent. The process is carried out in a fume hood under acidic conditions, and the yield is usually around 75-85%. The reaction is exothermic and requires careful control of temperature to prevent decomposition.

About

English Name (2,5-Difluorophenyl)hydrazine hydrochloride (1:1)
Molecular Formula C6H7ClF2N2
Molecular Weight 180.59 g/mol
SMILES C1=CC(=C(C=C1F)NN)F.Cl
InChIKey LZKLZCSHMDRKJH-UHFFFAOYSA-N
Last Updated: 2025-10-20 00:35

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