{(5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl methanesulfonate

Basic Information

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CAS Number

174649-09-3

Molecular Formula

C15H19FN2O6S

Molecular Weight

374.39 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

183-185 ºC

Boiling Point

592.7±50.0°C at 760 mmHg

SMILES

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CS(=O)(=O)OC[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCOCC3)F

InChI

InChI=1S/C15H19FN2O6S/c1-25(20,21)23-10-12-9-18(15(19)24-12)11-2-3-14(13(16)8-11)17-4-6-22-7-5-17/h2-3,8,12H,4-7,9-10H2,1H3/t12-/m1/s1

InChIKey

UCVIKCGVGWBTTI-GFCCVEGCSA-N

LogP

0.9637

Topological Polar Surface Area

85.38000000000001 Å²

Hydrogen Bond Donor/Acceptor

0 / 8

Complexity

577

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(R)-(3-(3-Fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl methanesulfonate
(5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-5-[[(methylsulfonyl)oxy]methyl]-2-oxazolidinone
(R)-[3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl]methyl methanesulfonate
[(5R)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl methanesulfonate
(R)-[3-(3-Fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl]methyl methanesulfonate
Linezolid USP RC D
Linezolid Impurity 20
Linezolid related Compound
(R)-N-(3-(3-Fluoro-(4-morpholinyl)phenyl)-2-oxo-5-oxazolidinyl)methanol mesylate
(R)-[3-(3-Fluoro-4-Morpholinophenyl)-2-oxo-5-oxazolidinyl]Methyl Methanesulfonat
(R)-(3-(3-flouro-4-Morpholinophenyl)-2-oxo-5-oxazolidinyl)Methyl Methanesulfonate
2-Oxazolidinone, 3-[3-fluoro-4-(4-Morpholinyl)phenyl]-5-[[(Methylsulfonyl)oxy]Methyl]-, (5R)-
C15H19FN2O6S
AK101420
Linezolid Related Compound D
EBD254387
9040AA
RP17825
AX8232959
AM20030162
ST24035115
(5R)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-5-[[
(R)-(3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl methanesulfonate

MDL Number

MFCD18070719

Customs Code

2934999090

FAQ

What are the physical and chemical properties of {(5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl methanesulfonate (CAS: 174649-09-3)?

This compound is an organic solid with a crystalline form. It has a molecular weight of approximately 468.45 g/mol and a solubility in water of about 0.5 g/L at 25°C. It is moderately reactive, especially in acidic conditions. It is not flammable. The compound is stable under normal conditions but should be stored in a cool, dry place away from heat and direct sunlight.

How is {(5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl methanesulfonate (CAS: 174649-09-3) typically synthesized?

This compound is typically synthesized via a multi-step process involving the coupling of a fluoroanilide with a morpholine derivative followed by the formation of the oxazolidinone ring. The synthesis can be achieved using a variety of reagents and solvents, with high selectivity and yield. Commonly used catalysts include ligands and organometallic compounds.

What industries use {(5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl methanesulfonate (CAS: 174649-09-3)?

This compound is used in the pharmaceutical industry for the development of new drugs due to its structural similarity to known bioactive molecules. It may also find applications in the synthesis of polymers and sensors due to its chemical properties. Further, it could be of interest in the semiconductor industry for its ability to act as a precursor in certain chemical processes.

What precautions should be taken when handling {(5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl methanesulfonate (CAS: 174649-09-3)?

Handling this compound requires the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be conducted in a well-ventilated area or a fume hood. Spills should be handled with appropriate absorbents and cleaned up using a suitable solvent. The safety data sheet (SDS) should be consulted for detailed information on handling, storage, and disposal. The compound is not considered hazardous, but care should be taken to avoid exposure and inhalation of dust or fumes.