Amoxicillin Trimer Impurity

Basic Information

View in Editor

CAS Number

174391-69-6

Molecular Formula

C48H57N9O15S3

Molecular Weight

1096.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

View in Editor

CC1([C@@H](N[C@H](S1)[C@@H](C(=O)N[C@H](c2ccc(cc2)O)C(=O)N[C@@H]([C@@H]3N[C@H](C(S3)(C)C)C(=O)O)C(=O)N[C@H](c4ccc(cc4)O)C(=O)N[C@H]5[C@@H]6N(C5=O)[C@H](C(S6)(C)C)C(=O)O)NC(=O)[C@@H](c7ccc(cc7)O)N)C(=O)O)C

InChI

InChI=1S/C48H57N9O15S3/c1-46(2)31(43(67)68)55-39(73-46)28(52-34(61)25(49)19-7-13-22(58)14-8-19)37(64)50-26(20-9-15-23(59)16-10-20)35(62)53-29(40-56-32(44(69)70)47(3,4)74-40)38(65)51-27(21-11-17-24(60)18-12-21)36(63)54-30-41(66)57-33(45(71)72)48(5,6)75-42(30)57/h7-18,25-33,39-40,42,55-56,58-60H,49H2,1-6H3,(H,50,64)(H,51,65)(H,52,61)(H,53,62)(H,54,63)(H,67,68)(H,69,70)(H,71,72)/t25-,26-,27-,28-,29-,30-,31+,32+,33+,39-,40-,42-/m1/s1

InChIKey

DJYKNXXZVZWXOK-SFUXYWTESA-N

LogP

-0.09189999999998882

Topological Polar Surface Area

388.47999999999996 Å²

Hydrogen Bond Donor/Acceptor

15 / 24

Synonyms & References

English

Amoxicillin Trimer
AMoxicillin TriMer
Amoxicillin Impurity 34
(2R,2'R,4S,4'S)-2,2'-((1R,4R,7R,10R,13R)-1-amino-14-(((2S,5R,6R)-2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptan-6-yl)amino)-1,7,13-tris(4-hydroxyphenyl)-2,5,8,11,14-pentaoxo-3,6,9,12-tetraazatetradecane-4,10-diyl)bis(5,5-dimethylthiazolidin
Amoxicillin Impurity M (EP) (n=3 Trimer)
Amoxicillin Impurity N (EP) (n=3 Trimer)
(2R,2'R,4S,4'S)-2,2'-((1R,4R,7R,10R,13R)-1-amino-14-(((2S,5R,6R)-2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptan-6-yl)amino)-1,7,13-tris(4-hydroxyphenyl)-2,5,8,11,14-pentaoxo-3,6,9,12-tetraazatetradecane-4,10-diyl)bis(5,5-dimethylthiazolidine-4-carboxylic acid)
Amoxicillin Impurity M(EP)
Amoxicillin EP impurity M

FAQ

What is Amoxicillin Trimer Impurity (CAS: 174391-69-6)?

Amoxicillin Trimer Impurity is a by-product of the synthesis of amoxicillin, an antibiotic used to treat bacterial infections. It does not have a distinct chemical formula as it is a mixture of trimeric impurities of amoxicillin. It has a molecular weight of approximately 879.9 g/mol. This impurity is characterized by its ability to interfere with the efficacy of amoxicillin, hence it is important to control its concentration in pharmaceutical formulations.

What are the main uses of Amoxicillin Trimer Impurity (CAS: 174391-69-6)?

Amoxicillin Trimer Impurity is not used in any specific application on its own. It is primarily of interest in the pharmaceutical industry as a quality control parameter. Its presence in amoxicillin formulations must be monitored to ensure the drug's efficacy and safety.

Is Amoxicillin Trimer Impurity (CAS: 174391-69-6) safe?

Amoxicillin Trimer Impurity is generally considered safe when present in trace amounts in amoxicillin formulations. However, high levels of this impurity can reduce the therapeutic efficacy of the drug and potentially cause adverse effects. It is important to adhere to the regulatory limits set by organizations like the FDA and EMA to ensure safe use.

How should Amoxicillin Trimer Impurity (CAS: 174391-69-6) be stored?

Amoxicillin Trimer Impurity should be stored in a cool, dry place, preferably at room temperature (15-30°C). It should be kept away from direct sunlight and moisture. The container should be tightly sealed to prevent degradation. It is advisable to store it in a dark-colored bottle to protect it from light exposure.