10-Hydroxy-8-methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic acid

Basic Information

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CAS Number

17413-38-6

Molecular Formula

C17H11NO8

Molecular Weight

357.27 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Powder

Melting Point

262-263 ºC

Solubility

Insuluble (1.5E-3 g/L) (25 ºC),

SMILES

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COc1cc(cc2c1cc(c3c2c4c(cc3C(=O)O)OCO4)[N+](=O)[O-])O

InChI

InChI=1S/C17H11NO8/c1-24-12-3-7(19)2-9-8(12)4-11(18(22)23)14-10(17(20)21)5-13-16(15(9)14)26-6-25-13/h2-5,19H,6H2,1H3,(H,20,21)

InChIKey

PADIFGYTAXNCRK-UHFFFAOYSA-N

LogP

3.56550

Complexity

580

Safety Information

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Storage Conditions

2-8℃

Synonyms & References

English

Phenanthro[3,4-d]-1,3-dioxole-5-carboxylicacid, 10-hydroxy-8-methoxy-6-nitro-
Aristolochic acid D
10-hydroxy-8-methoxy-6-nitronaphtho[2,1-g][1,3]benzodioxole-5-carboxylic acid
10-Hydroxy-8-methoxy-6-nitrophenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid
Aristolochic acid IVa
Aristolochic D
ARISTOLOCHIC ACID D(RG)(PLEASE CALL)
6-Nitro-8-methoxy-10-hydroxyphenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid
10-hydroxy-8-methoxy-6-nitro-naphtho[2,1-g][1,3]benzodioxole-5-carboxylic acid
Aristolochic acid-D
Aristolochic acid-IVa
MLS002473315
HMS2270M20
BDBM50306860
10-hydroxy-8-methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic acid
SMR001397396
10-Hydroxy-8-methoxy-6-nitrophenanthro[3,4-d]-1,

MDL Number

MFCD02751816

FAQ

What are the physical and chemical properties of 10-Hydroxy-8-methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic acid (CAS: 17413-38-6)?

10-Hydroxy-8-methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic acid is a crystalline solid with a molecular weight of approximately 372.14 g/mol. It has a low solubility in water but is soluble in organic solvents like acetone and ethyl acetate. Chemically, it is reactive and can undergo nitration and esterification reactions. It is stable under normal conditions but should be stored away from direct sunlight and heat.

How is 10-Hydroxy-8-methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic acid (CAS: 17413-38-6) typically synthesized?

10-Hydroxy-8-methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic acid is typically synthesized through a multi-step process involving nitration and hydroxylation of a phenanthro[3,4-d][1,3]dioxole derivative. Catalysts such as sulfuric acid are used, and the yield is moderate to good, around 70-80%, depending on the purity of starting materials and reaction conditions.

What industries use 10-Hydroxy-8-methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic acid (CAS: 17413-38-6)?

10-Hydroxy-8-methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic acid is primarily used in the pharmaceutical and chemical industries for the development of novel drugs and as an intermediate in the synthesis of other compounds. It also has potential applications in the polymer and sensor industries due to its unique chemical structure.

What precautions should be taken when handling 10-Hydroxy-8-methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic acid (CAS: 17413-38-6)?

When handling 10-Hydroxy-8-methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic acid, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood to avoid inhalation. In case of a spill, it should be cleaned up immediately using absorbent materials and the area should be flushed with water. Always consult the Material Safety Data Sheet (MSDS) or Safety Data Sheet (SDS) for specific handling and disposal instructions.