10-Hydroxy-8-methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic acid(CAS: 17413-38-6)

10-Hydroxy-8-methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic acid is a crystalline solid with a molecular weight of approximately 372.14 g/mol. It has a low solubility in water but is soluble in organic solvents like acetone and ethyl acetate. Chemically, it is reactive and can undergo nitration and esterification reactions. It is stable under normal conditions but should be stored away from direct sunlight and heat.

10-Hydroxy-8-methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic acid is typically synthesized through a multi-step process involving nitration and hydroxylation of a phenanthro[3,4-d][1,3]dioxole derivative. Catalysts such as sulfuric acid are used, and the yield is moderate to good, around 70-80%, depending on the purity of starting materials and reaction conditions.

10-Hydroxy-8-methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic acid is primarily used in the pharmaceutical and chemical industries for the development of novel drugs and as an intermediate in the synthesis of other compounds. It also has potential applications in the polymer and sensor industries due to its unique chemical structure.

When handling 10-Hydroxy-8-methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic acid, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood to avoid inhalation. In case of a spill, it should be cleaned up immediately using absorbent materials and the area should be flushed with water. Always consult the Material Safety Data Sheet (MSDS) or Safety Data Sheet (SDS) for specific handling and disposal instructions.