2-Oxa-6-Azaspiro[3.3]heptane

Basic Information

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CAS Number

174-78-7

Molecular Formula

C5H9NO

Molecular Weight

99.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

166 ºC

Flash Point

51 ºC

Refractive Index

1.4750 to 1.4790

SMILES

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C1C2(CN1)COC2

InChI

InChI=1S/C5H9NO/c1-5(2-6-1)3-7-4-5/h6H,1-4H2

InChIKey

HPJALMWOZYIZGE-UHFFFAOYSA-N

LogP

-0.39380000000000015

Topological Polar Surface Area

21.259999999999998 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

82.1

Safety Information

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Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class 3 Class 3

Synonyms & References

English

2-Oxa-6-azaspiro[3.3]heptane
BH270
FC0232
spiromorpholine
2-OXA-6-AZASPIRO[3.3]HEPTANE HCL
2-oxa-6-azaspiro[3.3]heptanes oxalate
2-oxa-6-azaspiro[3.3]heptanes (ForM: oxalate)
2-oxa-6-azaspiro[3,3]heptanes oxalic acid salt
2-Oxa-6-aza-spiro[3.3]heptane oxalic acid salt
2-oxa-6-aza-spiro[3.3]heptane
Spiro[oxetane-3,3'-azetidine]
2-oxa-6-azaspiro[3,3]heptane
HPJALMWOZYIZGE-UHFFFAOYSA-N
BCP06381
RP00265
NE64200
LS41150
BC254015
ST1020076
AB0040252
AM20020019
O0466
Y7837
BB 0261662
H112144
1
2-oxa-6-azaspiro[3.3]heptane

MDL Number

MFCD12407093

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 2-Oxa-6-Azaspiro[3.3]heptane (CAS: 174-78-7)?

2-Oxa-6-Azaspiro[3.3]heptane is a cyclic amine with a molecular weight of approximately 162.26 g/mol. It exists as a colorless, crystalline solid with a high melting point around 122°C. This compound is moderately soluble in water but has better solubility in organic solvents like methanol and ethanol. It shows moderate reactivity, exhibiting amine and alcohol functionalities that can participate in various chemical reactions.

How is 2-Oxa-6-Azaspiro[3.3]heptane (CAS: 174-78-7) typically synthesized?

2-Oxa-6-Azaspiro[3.3]heptane is synthesized via a Wittig reaction, typically using an appropriate aldehyde and a triphenylphosphine derivative. The reaction proceeds smoothly with good yield and selectivity, producing the desired cyclic amine. Catalysts such as triphenylphosphine are used to ensure high chemical efficiency and product purity.

What industries use 2-Oxa-6-Azaspiro[3.3]heptane (CAS: 174-78-7)?

2-Oxa-6-Azaspiro[3.3]heptane is utilized in pharmaceuticals for the synthesis of more complex molecules and in the polymer industry for functionalizing polymers. It also finds applications in the development of sensors and semiconductors due to its unique chemical properties and reactivity.

What precautions should be taken when handling 2-Oxa-6-Azaspiro[3.3]heptane (CAS: 174-78-7)?

When handling 2-Oxa-6-Azaspiro[3.3]heptane, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work under a fume hood to minimize exposure. Spills should be cleaned up with appropriate absorbents, and the area should be well-ventilated. Refer to the Safety Data Sheet (SDS) for detailed emergency procedures and storage conditions.