2-Oxa-6-Azaspiro[3.3]heptane(CAS: 174-78-7)

2-Oxa-6-Azaspiro[3.3]heptane is a cyclic amine with a molecular weight of approximately 162.26 g/mol. It exists as a colorless, crystalline solid with a high melting point around 122°C. This compound is moderately soluble in water but has better solubility in organic solvents like methanol and ethanol. It shows moderate reactivity, exhibiting amine and alcohol functionalities that can participate in various chemical reactions.

2-Oxa-6-Azaspiro[3.3]heptane is synthesized via a Wittig reaction, typically using an appropriate aldehyde and a triphenylphosphine derivative. The reaction proceeds smoothly with good yield and selectivity, producing the desired cyclic amine. Catalysts such as triphenylphosphine are used to ensure high chemical efficiency and product purity.

2-Oxa-6-Azaspiro[3.3]heptane is utilized in pharmaceuticals for the synthesis of more complex molecules and in the polymer industry for functionalizing polymers. It also finds applications in the development of sensors and semiconductors due to its unique chemical properties and reactivity.

When handling 2-Oxa-6-Azaspiro[3.3]heptane, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work under a fume hood to minimize exposure. Spills should be cleaned up with appropriate absorbents, and the area should be well-ventilated. Refer to the Safety Data Sheet (SDS) for detailed emergency procedures and storage conditions.