4-Chloropyridazine

Basic Information

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CAS Number

17180-92-6

Molecular Formula

C4H3ClN2

Molecular Weight

114.53 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

176.5-177.5 ºC

Boiling Point

241.7±13.0 ºC (760 Torr),

Flash Point

123.3±5.4 ºC,

SMILES

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C1=CN=NC=C1Cl

InChI

InChI=1S/C4H3ClN2/c5-4-1-2-6-7-3-4/h1-3H

InChIKey

VQRJGGJXFXWQRJ-UHFFFAOYSA-N

LogP

1.13

Topological Polar Surface Area

25.78 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

57.7

Synonyms & References

English

5-chloropyridazine
FT-0646950
4-Chloropyridazine
AB50535
AC-25150
17180-92-6
AKOS006330325
Pyridazine, 4-chloro-
BCP22404
Pyridazine,4-chloro-
CS-0030097
SCHEMBL221871
AMY24942
VQRJGGJXFXWQRJ-UHFFFAOYSA-N
J-515183
DTXSID90601424
4-Chloro-pyridazine
4-Chlor-pyridazin
Pyridazine,4-chloro

MDL Number

MFCD09264570

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 4-Chloropyridazine (CAS: 17180-92-6)?

4-Chloropyridazine is a crystalline solid with a molecular weight of 142.54 g/mol. It has a melting point of 158-159°C and is slightly soluble in water. It is reactive towards bases and exhibits moderate reactivity with nucleophiles. The compound is used in organic synthesis and as a starting material for the production of other compounds.

How is 4-Chloropyridazine (CAS: 17180-92-6) typically synthesized?

4-Chloropyridazine can be synthesized from pyridine chlorination. The chlorination is typically carried out using thionyl chloride as the reagent. The reaction is performed under anhydrous conditions to increase the yield and selectivity of the product. The process involves heating the mixture to a temperature of around 100°C and then purifying the product through recrystallization or distillation.

What industries use 4-Chloropyridazine (CAS: 17180-92-6)?

4-Chloropyridazine is used in the pharmaceutical industry as an intermediate for the synthesis of drugs. It is also used in the production of herbicides and dyes. Additionally, it can be utilized in the synthesis of other organic materials, such as polymers and sensors, due to its functional groups.

What precautions should be taken when handling 4-Chloropyridazine (CAS: 17180-92-6)?

Proper safety measures should be taken when handling 4-Chloropyridazine. It is recommended to wear personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The compound should be stored in a cool, dry place away from heat and ignition sources. In case of spill, it should be handled in a fume hood using appropriate absorbents and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.