Piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate

Basic Information

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CAS Number

171722-92-2

Molecular Formula

C18H20N2O2

Molecular Weight

296.37 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

SMILES

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C1CNCCC1OC(=O)NC2=CC=CC=C2C3=CC=CC=C3

InChI

InChI=1S/C18H20N2O2/c21-18(22-15-10-12-19-13-11-15)20-17-9-5-4-8-16(17)14-6-2-1-3-7-14/h1-9,15,19H,10-13H2,(H,20,21)

InChIKey

AGZCCVMWUZINGV-UHFFFAOYSA-N

LogP

3.6541000000000023

Topological Polar Surface Area

50.36 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

349

Synonyms & References

English

piperidin-4-yl biphenyl-2-ylcarbamate
carbamic acid, N-[1,1'-biphenyl]-2-yl-, 4-piperidinyl ester
LogP
piperidin-4-yl [1,1-biphenyl]-2-ylcarbamate
piperidin-4-yl N-(2-phenylphenyl)carbamate
16403-A2 ,9291
4-PIPERIDYL N-(2-BIPHENYL)CARBAMATE
piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate
Carbamic acid, N-[1,1'-biphenyl]-2-yl-, 4-piperidinyl ester-
SCHEMBL264806
AS-70404
Piperidin-4-yl [1,1 inverted exclamation mark -Biphenyl]-2-ylcarbamate
SY037709
DTXSID00445856
Biphenyl-2-yl-carbamic acid piperidin-4-yl ester
BDBM50337879
4-piperidyl n-(2-biphenyl)carbamate
Biphenyl-2-ylcarbamic Acid Piperidin-4-yl Ester
CHEMBL1683908
AMY16773
4-piperidyln-(2-biphenyl)carbamate
4-piperidyl N-(2-biphenylyl)carbamate
Biphenyl-2-ylcarbamic Acid Piperidin4-yl Ester
PIPERIDIN-4-YL N-{[1,1'-BIPHENYL]-2-YL}CARBAMATE
MFCD27964656
A927232
CS-0112922
Carbamic acid, [1,1'-biphenyl]-2-yl-, 4-piperidinyl ester
AKOS037646703
PIPERIDIN-4-YL N-(2-PHENYLPHENYL)CARBAMATE
171722-92-2

MDL Number

MFCD27964656

FAQ

What are the physical and chemical properties of Piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate (CAS: 171722-92-2)?

Piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate is a solid with a crystalline form. Its molecular weight is approximately 332.37 g/mol. The compound is slightly soluble in water but has good solubility in common organic solvents like methanol and dichloromethane. It is chemically stable but can react with strong acids or bases. It is important to handle this compound under anhydrous conditions to prevent hydrolysis.

How is Piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate (CAS: 171722-92-2) typically synthesized?

Piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate is typically synthesized through a multi-step process involving the coupling of 1,1'-biphenyl-2-amine with piperidine-4-carbaldehyde, followed by acylation. This process often uses a catalyst such as EDC and HOBT to enhance the coupling reaction. The overall yield is moderate, around 50-70%, depending on the purity of the starting materials and the reaction conditions.

What industries use Piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate (CAS: 171722-92-2)?

Piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate is used primarily in the pharmaceutical industry for its potential as a precursor in drug synthesis. It may also find applications in the development of sensors and as a component in certain polymer formulations. Due to its specific chemical properties, it is less commonly used in semiconductors or other industries.

What precautions should be taken when handling Piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate (CAS: 171722-92-2)?

When handling Piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate, it is crucial to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Handle the compound in a well-ventilated area or a fume hood to minimize exposure to airborne particles. Avoid contact with water and strong acids or bases, and store the compound in a cool, dry place away from direct sunlight. Always refer to the Safety Data Sheet (SDS) for detailed information on safe handling and disposal.