2-Methylalanyl-L-histidyl-3-(2-naphthyl)-D-alanyl-D-phenylalanyl-L-lysinamide | CAS No. 170851-70-4

2-Methylalanyl-L-histidyl-3-(2-naphthyl)-D-alanyl-D-phenylalanyl-L-lysinamide

Basic Information

CAS Number

170851-70-4

Molecular Formula

C38H49N9O5

Molecular Weight

711.87 g/mol

AD

Basic Physical Properties

CC(C)(C(=O)NC(CC1=CN=CN1)C(=O)NC(CC2=CC3=CC=CC=C3C=C2)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(CCCCN)C(=O)N)N

InChI

InChI=1S/C38H49N9O5/c1-38(2,41)37(52)47-32(21-28-22-42-23-43-28)36(51)46-31(20-25-15-16-26-12-6-7-13-27(26)18-25)35(50)45-30(19-24-10-4-3-5-11-24)34(49)44-29(33(40)48)14-8-9-17-39/h3-7,10-13,15-16,18,22-23,29-32H,8-9,14,17,19-21,39,41H2,1-2H3,(H2,40,48)(H,42,43)(H,44,49)(H,45,50)(H,46,51)(H,47,52)/t29-,30+,31+,32-/m0/s1

InChIKey

NEHWBYHLYZGBNO-BVEPWEIPSA-N

LogP

0.8816000000000053

Topological Polar Surface Area

240.21 Ų

Hydrogen Bond Donor/Acceptor

11 / 14

Complexity

1200

Synonyms & References

English

  • AMY25371
  • Aib-His-D-2-Nal-D-Phe-Lys-NH2
  • UNII-Y9M3S784Z6
  • Ipamorelin
  • Aib-His-2Nal-Phe-Lys-NH2
  • NS00071897
  • IPAMORELIN ACETATE
  • CHEMBL58547
  • Ipamorelin [INN]
  • AS-56185
  • IPAMORELIN [WHO-DD]
  • AKOS030573449
  • VGA85170
  • NNC 26-0161
  • NNC-260161
  • 2-Methylalanyl-L-histidyl-3-(2-naphthyl)-D-alanyl-D-phenylalanyl-L-lysinamide.
  • 170851-70-4
  • DB12370
  • NNC-26-0161
  • SCHEMBL8169698
  • Y9M3S784Z6
  • NCGC00167295-01
  • 2-Methylalanyl-L-histidyl-3-(2-naphthyl)-D-alanyl-D-phenylalanyl-L-lysinamide
  • SCHEMBL183305
  • L-Lysinamide,2-methylalanyl-L-histidyl-3-(2-naphthalenyl)-D-alanyl-D-phenylalanyl-
  • Candida utilis
  • ipamorelin
  • ipamorelin(10mg)
  • ipamorelin(1mg)
  • ipamorelin(2mg)
  • ipamorelin(5mg)

MDL Number

MFCD02179658

FAQ

What are the physical and chemical properties of 2-Methylalanyl-L-histidyl-3-(2-naphthyl)-D-alanyl-D-phenylalanyl-L-lysinamide (CAS: 170851-70-4)?

The compound 2-Methylalanyl-L-histidyl-3-(2-naphthyl)-D-alanyl-D-phenylalanyl-L-lysinamide is a crystalline solid with a molecular weight of approximately 901.34 g/mol. It has a high solubility in organic solvents such as dimethyl sulfoxide (DMSO) and poor solubility in water. The compound exhibits moderate reactivity towards nucleophiles and can be used in various chemical reactions. It is stable under normal storage conditions but should be protected from moisture and strong acids or bases.

How is 2-Methylalanyl-L-histidyl-3-(2-naphthyl)-D-alanyl-D-phenylalanyl-L-lysinamide (CAS: 170851-70-4) typically synthesized?

2-Methylalanyl-L-histidyl-3-(2-naphthyl)-D-alanyl-D-phenylalanyl-L-lysinamide is typically synthesized through solid-phase peptide synthesis (SPPS) or solution-phase peptide synthesis. The synthesis involves coupling of amino acids using Fmoc (9-fluorenylmethyloxycarbonyl) chemistry, which provides excellent control over sequence ordering and selectivity. The overall yield is generally moderate to high, depending on the specific reaction conditions and purity of reagents used.

What industries use 2-Methylalanyl-L-histidyl-3-(2-naphthyl)-D-alanyl-D-phenylalanyl-L-lysinamide (CAS: 170851-70-4)?

2-Methylalanyl-L-histidyl-3-(2-naphthyl)-D-alanyl-D-phenylalanyl-L-lysinamide is primarily used in the pharmaceutical industry due to its potential as a drug candidate for various diseases. It may also be utilized in polymer chemistry for developing novel materials with specific properties. Additionally, this compound can be employed in the development of sensors and semiconductors, although its specific applications in these areas are limited compared to the pharmaceutical sector.

What precautions should be taken when handling 2-Methylalanyl-L-histidyl-3-(2-naphthyl)-D-alanyl-D-phenylalanyl-L-lysinamide (CAS: 170851-70-4)?

When handling 2-Methylalanyl-L-histidyl-3-(2-naphthyl)-D-alanyl-D-phenylalanyl-L-lysinamide, it is essential to follow standard laboratory safety practices. Wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Work in a well-ventilated area, preferably in a fume hood, to minimize exposure to the compound. If a spill occurs, immediately clean it up using appropriate absorbent materials and dispose of the waste according to local regulations. Refer to the Safety Data Sheet (SDS) for specific handling and storage instructions.

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