Compound Q&A
How is 2-Methylalanyl-L-histidyl-3-(2-naphthyl)-D-alanyl-D-phenylalanyl-L-lysinamide (CAS: 170851-70-4) typically synthesized?
Answer
2-Methylalanyl-L-histidyl-3-(2-naphthyl)-D-alanyl-D-phenylalanyl-L-lysinamide is typically synthesized through solid-phase peptide synthesis (SPPS) or solution-phase peptide synthesis. The synthesis involves coupling of amino acids using Fmoc (9-fluorenylmethyloxycarbonyl) chemistry, which provides excellent control over sequence ordering and selectivity. The overall yield is generally moderate to high, depending on the specific reaction conditions and purity of reagents used.
About
CAS No
170851-70-4
English Name
2-Methylalanyl-L-histidyl-3-(2-naphthyl)-D-alanyl-D-phenylalanyl-L-lysinamide
Molecular Formula
C38H49N9O5
Molecular Weight
711.87 g/mol
SMILES
CC(C)(C(=O)NC(CC1=CN=CN1)C(=O)NC(CC2=CC3=CC=CC=C3C=C2)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(CCCCN)C(=O)N)N
InChIKey
NEHWBYHLYZGBNO-BVEPWEIPSA-N
Last Updated: 2025-10-13 17:50
