6-Chloro-5-methyl-3(2H)-pyridazinone

Basic Information

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CAS Number

1703-07-7

Molecular Formula

C5H5ClN2O

Molecular Weight

144.56 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

SMILES

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CC1=CC(=O)NN=C1Cl

InChI

InChI=1S/C5H5ClN2O/c1-3-2-4(9)7-8-5(3)6/h2H,1H3,(H,7,9)

InChIKey

UGDOVAWXAHZLEV-UHFFFAOYSA-N

LogP

1.1440199999999998

Topological Polar Surface Area

46.010000000000005 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

207

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

1703-07-7
SCHEMBL14123454
SY107824
1822677-94-0
6-Chloro-3-hydroxy-5-methylpyridazine
J-518593
3-chloro-4-methyl-1H-pyridazin-6-one
SCHEMBL957290
6-chloro-5-methylpyridazin-3(2h)-one
AKOS006346521
A882028
AKOS022634169
CS-W019006
6-Chloro-5-methyl-3(2H)-pyridazinone
GS-3956
3(2H)-Pyridazinone, 6-chloro-5-methyl-
FT-0688714
AMY25057
6-Chloro-5-methylpyridazin-3-ol
DTXSID10168827
6-chloro-5-methyl-2,3-dihydropyridazin-3-one
6-CHLORO-5-METHYL-2H-PYRIDAZIN-3-ONE
MFCD04971427
6-Chloro-5-methylpyridazin-3(2H)-one
3(2H)-Pyridazinone,6-chloro-5-methyl-
6-Chloro-5-methylpyridazin-3-ol, 6-Chloro-3-hydroxy-5-methyl-1,2-diazine

MDL Number

MFCD04971427

FAQ

What are the physical and chemical properties of 6-Chloro-5-methyl-3(2H)-pyridazinone (CAS: 1703-07-7)?

6-Chloro-5-methyl-3(2H)-pyridazinone is a crystalline solid with a molecular weight of approximately 180.67 g/mol. It has a solubility of 200 mg/L in water at 25°C. Chemically, it is relatively stable and less reactive in acidic and neutral media but can be sensitive to strong bases and reducing agents.

How is 6-Chloro-5-methyl-3(2H)-pyridazinone (CAS: 1703-07-7) typically synthesized?

6-Chloro-5-methyl-3(2H)-pyridazinone can be synthesized via the condensation of 5-methyl-3-pyridazinone with thionyl chloride in the presence of a suitable base such as pyridine. The reaction is carried out in anhydrous conditions to enhance selectivity and yield.

What industries use 6-Chloro-5-methyl-3(2H)-pyridazinone (CAS: 1703-07-7)?

6-Chloro-5-methyl-3(2H)-pyridazinone is used in the pharmaceutical industry for the synthesis of certain drugs, particularly as an intermediate in the development of anti-inflammatory and anticonvulsant medications. It also finds application in the chemical industry for the production of dyes and pigments.

What precautions should be taken when handling 6-Chloro-5-methyl-3(2H)-pyridazinone (CAS: 1703-07-7)?

Handling 6-Chloro-5-methyl-3(2H)-pyridazinone requires the use of personal protective equipment (PPE) such as gloves and goggles. Store it in a well-ventilated area and avoid exposure to moisture and strong bases. In case of spillage, handle with care and use appropriate safety data sheets (SDS) for guidelines on spill treatment and disposal.