6-Chloro-5-methyl-3(2H)-pyridazinone(CAS: 1703-07-7)

6-Chloro-5-methyl-3(2H)-pyridazinone is a crystalline solid with a molecular weight of approximately 180.67 g/mol. It has a solubility of 200 mg/L in water at 25°C. Chemically, it is relatively stable and less reactive in acidic and neutral media but can be sensitive to strong bases and reducing agents.

6-Chloro-5-methyl-3(2H)-pyridazinone can be synthesized via the condensation of 5-methyl-3-pyridazinone with thionyl chloride in the presence of a suitable base such as pyridine. The reaction is carried out in anhydrous conditions to enhance selectivity and yield.

6-Chloro-5-methyl-3(2H)-pyridazinone is used in the pharmaceutical industry for the synthesis of certain drugs, particularly as an intermediate in the development of anti-inflammatory and anticonvulsant medications. It also finds application in the chemical industry for the production of dyes and pigments.

Handling 6-Chloro-5-methyl-3(2H)-pyridazinone requires the use of personal protective equipment (PPE) such as gloves and goggles. Store it in a well-ventilated area and avoid exposure to moisture and strong bases. In case of spillage, handle with care and use appropriate safety data sheets (SDS) for guidelines on spill treatment and disposal.