2-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}-1-[(4-methylphenyl)sulfonyl]ethanol | CAS No. 168640-82-2
2-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}-1-[(4-methylphenyl)sulfonyl]ethanol
Basic Information
CAS Number
168640-82-2
Molecular Formula
C15H23N3O6S
Molecular Weight
373.42 g/mol
AD
Basic Physical Properties
Synonyms & References
English
- 2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol
- Azido-PEG4-Tos
- 2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate
- 11-Azido-3,6,9-trioxaundecanyl p-toluenesulfonate
- N3-PEG4-Tos
- Azido-PEG4-OTs
- N3-PEG4-OTs
- N3-PEG4-Tos/Ethanol, 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-, 1-(4-methylbenzenesulfonate)
- Ethanol,2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-, 1-(4-methylbenzenesulfonate)
- 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-1-(2-methylphenyl)sulfonylethanol
- 2-[2-[2-(2-AZIDOETHOXY)ETHOXY]ETHOXY]-1-(P-TOLUENESULFONYL)-ETHANOL
- 11-azido-3,6,9-trioxa-undecanyl p-toluenesulfonate
- 2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl 4-methylbenzenesulfonate
- 2-{2-[2-(2-azido-ethoxy)-ethoxy]-ethoxy}-ethyl tosylate
- toluene-4-sulfonic acid 2-{2-[2-(2-azidoethoxy)ethoxy]ethoxy}ethyl ester
- Azide-PEG4-Tos
MDL Number
MFCD30347788
FAQ
What are the physical and chemical properties of 2-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}-1-[(4-methylphenyl)sulfonyl]ethanol (CAS: 168640-82-2)?
2-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}-1-[(4-methylphenyl)sulfonyl]ethanol is a colorless to slightly yellowish crystalline solid with a molecular weight of approximately 534.55 g/mol. It is poorly soluble in water but soluble in common organic solvents such as ethanol, methanol, and dimethyl sulfoxide. Chemically, it is highly reactive due to the azido group, making it susceptible to reduction and decomposition. It has a high melting point and is stable under normal conditions but requires careful handling due to its reactivity.
How is 2-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}-1-[(4-methylphenyl)sulfonyl]ethanol (CAS: 168640-82-2) typically synthesized?
2-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}-1-[(4-methylphenyl)sulfonyl]ethanol is typically synthesized using a multi-step process involving the protection of the hydroxyl groups, followed by the introduction of the azido group, and then the coupling with the sulfonyl chloride. This synthesis often requires the use of protecting agents and careful control of reaction conditions to achieve high yield and selectivity. Common catalysts include Lewis acids and base-mediated reactions.
What industries use 2-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}-1-[(4-methylphenyl)sulfonyl]ethanol (CAS: 168640-82-2)?
2-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}-1-[(4-methylphenyl)sulfonyl]ethanol is primarily used in pharmaceuticals for its azido functionality, which can be used in drug synthesis and as a building block for more complex molecules. It is also used in the polymer industry for unique chemical modification of polymers, and in the semiconductor industry for its use in photoresists and other advanced materials. Additionally, it finds applications in sensing technologies due to its reactivity.
What precautions should be taken when handling 2-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}-1-[(4-methylphenyl)sulfonyl]ethanol (CAS: 168640-82-2)?
When handling 2-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}-1-[(4-methylphenyl)sulfonyl]ethanol, it is crucial to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Ensure the use of a fume hood to minimize inhalation risks. Spills should be cleaned up with care, using absorbent materials, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed information and emergency procedures. Storage should be in a cool, dry place, away from heat and direct sunlight.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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