6-Bromo-1',3',3'-trimethyl-1',3'-dihydrospiro[chromene-2,2'-indole] | CAS No. 16650-14-9

6-Bromo-1',3',3'-trimethyl-1',3'-dihydrospiro[chromene-2,2'-indole]

Basic Information

CAS Number

16650-14-9

Molecular Formula

C19H18BrNO

Molecular Weight

356.26 g/mol

AD

Basic Physical Properties

CC1(C2=CC=CC=C2N(C13C=CC4=C(O3)C=CC(=C4)Br)C)C

InChI

InChI=1S/C19H18BrNO/c1-18(2)15-6-4-5-7-16(15)21(3)19(18)11-10-13-12-14(20)8-9-17(13)22-19/h4-12H,1-3H3

InChIKey

BDULIJWZMMHIEQ-UHFFFAOYSA-N

LogP

4.978600000000005

Topological Polar Surface Area

12.47 Ų

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

476

Synonyms & References

English

  • 6-bromo-1',3',3'-trimethyl-1',3'-dihydrospiro[chromene-2,2'-indole]
  • SR-01000391122
  • 6-Bromo-1',3',3'-trimethylspiro[chromene-2,2'-indoline]
  • AKOS021983628
  • 1,3,3-Trimethylindolino-6/'-bromobenzopyrylospiran
  • BDULIJWZMMHIEQ-UHFFFAOYSA-N
  • Spiro[2H-1-benzopyran-2,2'-[2H]indole], 6-bromo-1',3'-dihydro-1',3',3'-trimethyl-
  • 16650-14-9
  • J-010290
  • T71896
  • 1,3,3-Trimethylindolino-6'-bromobenzopyrylospiran, [Photochromic Compound]
  • 6-bromo-1',3',3'-trimethylspiro[chromene-2,2'-indole]
  • DTXSID50344143
  • CS-0316439
  • SCHEMBL4628824
  • AKOS000513776
  • 1',3'-dihydro-1',3',3'-trimethyl-6-bromo-spiro[2h-1-benzopyran-2,2'-[2h]indole]
  • 6-Bromo-1',3',3'-trimethylspiro[1(2H)-benzopyran-2,2'-indoline]
  • AS-73816
  • Oprea1_327169
  • FT-0711586
  • SR-01000391122-1
  • 1,3,3-Trimethylindolino-6'-bromobenzopyrylospiran [Photochromic Compound]
  • SB64084
  • Oprea1_242374
  • T0370
  • 1,3,3-Trimethylindolino-6'-bromobenzopyrylospiran
  • MFCD00059896
  • Spiro[2H-1-benzopyran-2,2'-[2H]indole],6-bromo-1',3'-dihydro-1',3',3'-trimethyl-
  • 6-Brom-1',3',3'-trimethyl-2',3'-dihydro-2H-benzo<b>pyran-2-spiro-2'-indol
  • 6'-Brom-1,3,3-trimethyl-indolin-2-spiro-2'-<2H-1>benzopyran

MDL Number

MFCD00059896

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 6-Bromo-1',3',3'-trimethyl-1',3'-dihydrospiro[chromene-2,2'-indole] (CAS: 16650-14-9)?

6-Bromo-1',3',3'-trimethyl-1',3'-dihydrospiro[chromene-2,2'-indole] is a solid crystalline compound with a high molecular weight. It has low water solubility but good solubility in organic solvents such as dichloromethane and acetone. The compound exhibits moderate reactivity towards nucleophiles and is stable under normal laboratory conditions. It has a distinctive chemical structure that makes it useful in various synthetic applications.

How is 6-Bromo-1',3',3'-trimethyl-1',3'-dihydrospiro[chromene-2,2'-indole] (CAS: 16650-14-9) typically synthesized?

6-Bromo-1',3',3'-trimethyl-1',3'-dihydrospiro[chromene-2,2'-indole] is typically synthesized via a multistep reaction involving the bromination of a precursor spiro compound followed by a cyclization step. The reaction is catalyzed by phase transfer catalysts and proceeds with high selectivity and yield, making it a suitable method for industrial-scale production.

What industries use 6-Bromo-1',3',3'-trimethyl-1',3'-dihydrospiro[chromene-2,2'-indole] (CAS: 16650-14-9)?

6-Bromo-1',3',3'-trimethyl-1',3'-dihydrospiro[chromene-2,2'-indole] is used in the pharmaceutical industry for the synthesis of bioactive molecules, as well as in the semiconductor industry for its unique electronic properties. It is also applied in the development of sensor technologies due to its photochromic behavior.

What precautions should be taken when handling 6-Bromo-1',3',3'-trimethyl-1',3'-dihydrospiro[chromene-2,2'-indole] (CAS: 16650-14-9)?

When handling 6-Bromo-1',3',3'-trimethyl-1',3'-dihydrospiro[chromene-2,2'-indole], it is essential to use appropriate personal protective equipment such as gloves and a lab coat. Work should be conducted in a fume hood to minimize exposure. In case of a spill, it should be cleaned up promptly using appropriate techniques and materials. Always refer to the Safety Data Sheet (SDS) for detailed information and emergency procedures.

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