Compound Q&A

How is 6-Bromo-1',3',3'-trimethyl-1',3'-dihydrospiro[chromene-2,2'-indole] (CAS: 16650-14-9) typically synthesized?

Answer

6-Bromo-1',3',3'-trimethyl-1',3'-dihydrospiro[chromene-2,2'-indole]
6-Bromo-1',3',3'-trimethyl-1',3'-dihydrospiro[chromene-2,2'-indole] is typically synthesized via a multistep reaction involving the bromination of a precursor spiro compound followed by a cyclization step. The reaction is catalyzed by phase transfer catalysts and proceeds with high selectivity and yield, making it a suitable method for industrial-scale production.

About

CAS No 16650-14-9
English Name 6-Bromo-1',3',3'-trimethyl-1',3'-dihydrospiro[chromene-2,2'-indole]
Molecular Formula C19H18BrNO
Molecular Weight 356.26 g/mol
SMILES CC1(C2=CC=CC=C2N(C13C=CC4=C(O3)C=CC(=C4)Br)C)C
InChIKey BDULIJWZMMHIEQ-UHFFFAOYSA-N
Last Updated: 2025-11-27 19:31

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