2-Chloro-4,5-difluorobenzaldehyde

Basic Information

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CAS Number

165047-23-4

Molecular Formula

C7H3ClF2O

Molecular Weight

176.55 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Aldehydes

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Boiling Point

211.9±35.0 ºC (760 Torr),

Flash Point

81.9±25.9 ºC,

SMILES

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C1=C(C(=CC(=C1F)F)Cl)C=O

InChI

InChI=1S/C7H3ClF2O/c8-5-2-7(10)6(9)1-4(5)3-11/h1-3H

InChIKey

GWUMAKZIHXGJKC-UHFFFAOYSA-N

LogP

2.4307000000000007

Topological Polar Surface Area

17.07 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

153

Synonyms & References

English

DS-1634
A810618
FT-0736359
2-CHLORO-4,5-DIFLUOROBENZALDEHYDE
CS-W021648
2-chloro-4,5-difluoro-benzaldehyde
MFCD07782050
Benzaldehyde,2-chloro-4,5-difluoro-
SCHEMBL1053001
165047-23-4
GWUMAKZIHXGJKC-UHFFFAOYSA-N
AKOS006284687
AM62286
SY060418
J-508709
DTXSID90571097
2-Chloro-4,5-difluorobenzaldehyde
Benzaldehyde, 2-chloro-4,5-difluoro-
PubChem1429
AS04974
VZ24208
LF10680
RP23818
CM11869
AS05546
2-chloranyl-4,5-bis(fluoranyl)benzaldehyde
AB0005362
ST24032432
W3595

MDL Number

MFCD07782050

Customs Code

2913000090

FAQ

What are the physical and chemical properties of 2-Chloro-4,5-difluorobenzaldehyde (CAS: 165047-23-4)?

2-Chloro-4,5-difluorobenzaldehyde (CAS: 165047-23-4) is a crystalline compound with a molecular weight of approximately 219.02 g/mol. It has a melting point of 114-117°C and is slightly soluble in water. This compound is reactive towards nucleophiles and exhibits aromatic properties typical of aldehyde functional groups. It is used in synthesis of various compounds and as an intermediate in the pharmaceutical industry.

How is 2-Chloro-4,5-difluorobenzaldehyde (CAS: 165047-23-4) typically synthesized?

2-Chloro-4,5-difluorobenzaldehyde (CAS: 165047-23-4) is typically synthesized via the reduction of 2-chloro-4,5-difluorobenzoic acid with a suitable reducing agent such as lithium aluminum hydride (LAH). The process involves careful control of reaction conditions to ensure high yield and selectivity. Common solvents include THF or DCM, and the reaction is conducted in a fume hood due to the generation of hydrogen gas.

What industries use 2-Chloro-4,5-difluorobenzaldehyde (CAS: 165047-23-4)?

2-Chloro-4,5-difluorobenzaldehyde (CAS: 165047-23-4) is used in a variety of industries, including pharmaceuticals, where it serves as an intermediary in the production of drugs. It is also utilized in the synthesis of functional materials and polymers, as well as in the development of sensors and semiconductors due to its aromatic and aldehyde properties.

What precautions should be taken when handling 2-Chloro-4,5-difluorobenzaldehyde (CAS: 165047-23-4)?

When handling 2-Chloro-4,5-difluorobenzaldehyde (CAS: 165047-23-4), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. The substance should be used in a well-ventilated area or a fume hood to minimize inhalation risk. In case of a spill, use appropriate clean-up materials and ensure the area is well-ventilated. Refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.