2-Chloro-4,5-difluorobenzaldehyde(CAS: 165047-23-4)

2-Chloro-4,5-difluorobenzaldehyde (CAS: 165047-23-4) is a crystalline compound with a molecular weight of approximately 219.02 g/mol. It has a melting point of 114-117°C and is slightly soluble in water. This compound is reactive towards nucleophiles and exhibits aromatic properties typical of aldehyde functional groups. It is used in synthesis of various compounds and as an intermediate in the pharmaceutical industry.

2-Chloro-4,5-difluorobenzaldehyde (CAS: 165047-23-4) is typically synthesized via the reduction of 2-chloro-4,5-difluorobenzoic acid with a suitable reducing agent such as lithium aluminum hydride (LAH). The process involves careful control of reaction conditions to ensure high yield and selectivity. Common solvents include THF or DCM, and the reaction is conducted in a fume hood due to the generation of hydrogen gas.

2-Chloro-4,5-difluorobenzaldehyde (CAS: 165047-23-4) is used in a variety of industries, including pharmaceuticals, where it serves as an intermediary in the production of drugs. It is also utilized in the synthesis of functional materials and polymers, as well as in the development of sensors and semiconductors due to its aromatic and aldehyde properties.

When handling 2-Chloro-4,5-difluorobenzaldehyde (CAS: 165047-23-4), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. The substance should be used in a well-ventilated area or a fume hood to minimize inhalation risk. In case of a spill, use appropriate clean-up materials and ensure the area is well-ventilated. Refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.