Methyl 5-amino-1-benzofuran-2-carboxylate | CAS No. 1646-29-3

Methyl 5-amino-1-benzofuran-2-carboxylate

Basic Information

CAS Number

1646-29-3

Molecular Formula

C10H9NO3

Molecular Weight

191.19 g/mol

AD

Basic Physical Properties

COC(=O)C1=CC2=C(O1)C=CC(=C2)N

InChI

InChI=1S/C10H9NO3/c1-13-10(12)9-5-6-4-7(11)2-3-8(6)14-9/h2-5H,11H2,1H3

InChIKey

OLLMSIUDBMURHQ-UHFFFAOYSA-N

LogP

1.8015999999999999

Topological Polar Surface Area

65.46000000000001 Ų

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

231

Synonyms & References

English

  • SY045668
  • 2-Methoxycarbonyl-5-aminobenzofuran
  • AC4642
  • 2-Benzofurancarboxylic acid, 5-amino-, methyl ester
  • 5-amino-2-methoxycarbonylbenzofuran
  • FT-0693567
  • 5-aminobenzofuran-2-carboxylic acid methyl ester
  • Methyl 5-aminobenzofuran-2-carboxylate
  • DTXSID80445677
  • 5-amino-2-(methoxycarbonyl)benzofuran
  • AKOS009481029
  • EN300-41647
  • MFCD07368331
  • 5-AMINO-BENZOFURAN-2-CARBOXYLIC ACID METHYL ESTER
  • OLLMSIUDBMURHQ-UHFFFAOYSA-N
  • SCHEMBL211674
  • 1646-29-3
  • methyl 5-amino-1-benzofuran-2-carboxylate
  • methyl 5-aminobenzofuran-2-carboxylate
  • 2-Benzofurancarboxylicacid, 5-amino-, methyl ester
  • 5-Amino-benzofuran-2-carbonsaeure-methylester
  • 5-Amino-cumarilsaeure-methylester

MDL Number

MFCD07368331

Customs Code

2932999099

FAQ

What are the physical and chemical properties of Methyl 5-amino-1-benzofuran-2-carboxylate (CAS: 1646-29-3)?

Methyl 5-amino-1-benzofuran-2-carboxylate (CAS: 1646-29-3) is a crystalline solid with a molecular weight of approximately 226.24 g/mol. It has a solubility in water of about 1.5 g/L at 25°C. This compound is relatively stable under normal conditions but reacts with strong bases. It is used in organic synthesis and pharmaceuticals.

How is Methyl 5-amino-1-benzofuran-2-carboxylate (CAS: 1646-29-3) typically synthesized?

Methyl 5-amino-1-benzofuran-2-carboxylate (CAS: 1646-29-3) is typically synthesized via the condensation of methyl 2-benzofuran-2-carboxylate with aniline. The reaction is catalyzed by a strong acid, and the choice of catalyst affects the selectivity and yield of the product. High purity is achieved through recrystallization from an appropriate solvent.

What industries use Methyl 5-amino-1-benzofuran-2-carboxylate (CAS: 1646-29-3)?

Methyl 5-amino-1-benzofuran-2-carboxylate (CAS: 1646-29-3) is used in the pharmaceutical industry for the synthesis of various drug candidates. It is also utilized in polymer chemistry for developing new materials and in sensor technology for its unique chemical reactivity.

What precautions should be taken when handling Methyl 5-amino-1-benzofuran-2-carboxylate (CAS: 1646-29-3)?

When handling Methyl 5-amino-1-benzofuran-2-carboxylate (CAS: 1646-29-3), wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Store it in a cool, dry place away from heat and direct sunlight. Use a fume hood during handling and disposal. Disposal should be in accordance with local regulations, and always consult the Safety Data Sheet (SDS) for detailed information.

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