Methyl 5-amino-1-benzofuran-2-carboxylate(CAS: 1646-29-3)

Methyl 5-amino-1-benzofuran-2-carboxylate (CAS: 1646-29-3) is a crystalline solid with a molecular weight of approximately 226.24 g/mol. It has a solubility in water of about 1.5 g/L at 25°C. This compound is relatively stable under normal conditions but reacts with strong bases. It is used in organic synthesis and pharmaceuticals.

Methyl 5-amino-1-benzofuran-2-carboxylate (CAS: 1646-29-3) is typically synthesized via the condensation of methyl 2-benzofuran-2-carboxylate with aniline. The reaction is catalyzed by a strong acid, and the choice of catalyst affects the selectivity and yield of the product. High purity is achieved through recrystallization from an appropriate solvent.

Methyl 5-amino-1-benzofuran-2-carboxylate (CAS: 1646-29-3) is used in the pharmaceutical industry for the synthesis of various drug candidates. It is also utilized in polymer chemistry for developing new materials and in sensor technology for its unique chemical reactivity.

When handling Methyl 5-amino-1-benzofuran-2-carboxylate (CAS: 1646-29-3), wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Store it in a cool, dry place away from heat and direct sunlight. Use a fume hood during handling and disposal. Disposal should be in accordance with local regulations, and always consult the Safety Data Sheet (SDS) for detailed information.