(2,5-dimethyl-3-thienyl)boronic acid

Basic Information

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CAS Number

162607-23-0

Molecular Formula

C6H9BO2S

Molecular Weight

156.02 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

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B(C1=C(SC(=C1)C)C)(O)O

InChI

InChI=1S/C6H9BO2S/c1-4-3-6(7(8)9)5(2)10-4/h3,8-9H,1-2H3

InChIKey

RFQHMNWNEOZRLK-UHFFFAOYSA-N

LogP

0.04474

Topological Polar Surface Area

40.46 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

120

Synonyms & References

English

162607-23-0
DTXSID10670556
RFQHMNWNEOZRLK-UHFFFAOYSA-N
(2,5-dimethylthiophen-3-yl)boronic acid
(2,5-dimethylthiophen-3-yl)boronicacid
SY123487
(2,5-dimethyl-3-thienyl)boronic acid
Boronic acid, (2,5-dimethyl-3-thienyl)-
PS-13019
CS-0038853
SCHEMBL498281
CHEMBL3236897
BCP20264
AM803288
2,5-dimethylthiophen-3-ylboronic acid
EN300-251472
2,5-Dimethylthiophene-3-boronic acid
MFCD09837620
AKOS006280327
Z1198233978
AC-33582
Boronic acid,B-(2,5-dimethyl-3-thienyl)-
2,5-Dimethylthiophene-3-Boronic Acid
2,5-Dimethyl-3-thienylboronic acid
2,5-dimethylthiene-3-yl boronic acid
2,5-dimethylthiophen-3-yl boronic acid
QC-5988
(2,5-Dimethyl-3-thienyl)boronic acid

MDL Number

MFCD09837620

FAQ

What are the physical and chemical properties of (2,5-dimethyl-3-thienyl)boronic acid (CAS: 162607-23-0)?

(2,5-dimethyl-3-thienyl)boronic acid is a solid with a crystalline form. It has a molecular weight of approximately 237.26 g/mol and is slightly soluble in water. Chemically, it is reactive towards nucleophiles and can participate in various synthetic reactions. It is also known for its ability to form coordination compounds with transition metals.

How is (2,5-dimethyl-3-thienyl)boronic acid (CAS: 162607-23-0) typically synthesized?

(2,5-dimethyl-3-thienyl)boronic acid can be synthesized via the reaction of 2,5-dimethylthiophene with boron tribromide in the presence of a base. The process involves the deprotonation and subsequent boronation of the thiophene ring. This method provides good selectivity and yield, typically in the range of 70-90%.

What industries use (2,5-dimethyl-3-thienyl)boronic acid (CAS: 162607-23-0)?

(2,5-dimethyl-3-thienyl)boronic acid is used in various industries. It is particularly important in the pharmaceutical industry for drug synthesis, in semiconductor manufacturing for its use in photoresists, and in the polymer industry for its role as a monomer. Additionally, it is used in sensor technology and as an intermediate in the synthesis of other boronic acids and esters.

What precautions should be taken when handling (2,5-dimethyl-3-thienyl)boronic acid (CAS: 162607-23-0)?

When handling (2,5-dimethyl-3-thienyl)boronic acid, safety goggles and gloves should be worn. It is recommended to conduct experiments in a well-ventilated area or fume hood to avoid inhalation of dust. Spills should be cleaned up using appropriate absorbent materials. The material safety data sheet (MSDS) should be consulted for detailed safety information and emergency response guidelines.