(2,5-dimethyl-3-thienyl)boronic acid(CAS: 162607-23-0)

(2,5-dimethyl-3-thienyl)boronic acid is a solid with a crystalline form. It has a molecular weight of approximately 237.26 g/mol and is slightly soluble in water. Chemically, it is reactive towards nucleophiles and can participate in various synthetic reactions. It is also known for its ability to form coordination compounds with transition metals.

(2,5-dimethyl-3-thienyl)boronic acid can be synthesized via the reaction of 2,5-dimethylthiophene with boron tribromide in the presence of a base. The process involves the deprotonation and subsequent boronation of the thiophene ring. This method provides good selectivity and yield, typically in the range of 70-90%.

(2,5-dimethyl-3-thienyl)boronic acid is used in various industries. It is particularly important in the pharmaceutical industry for drug synthesis, in semiconductor manufacturing for its use in photoresists, and in the polymer industry for its role as a monomer. Additionally, it is used in sensor technology and as an intermediate in the synthesis of other boronic acids and esters.

When handling (2,5-dimethyl-3-thienyl)boronic acid, safety goggles and gloves should be worn. It is recommended to conduct experiments in a well-ventilated area or fume hood to avoid inhalation of dust. Spills should be cleaned up using appropriate absorbent materials. The material safety data sheet (MSDS) should be consulted for detailed safety information and emergency response guidelines.