2-Methyl-2-propanyl 3-(aminomethyl)-1-piperidinecarboxylate

Basic Information

View in Editor

CAS Number

162167-97-7

Molecular Formula

C11H22N2O2

Molecular Weight

214.31 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Colorless to Yellow Liquid

Boiling Point

299.4℃ at 760 mmHg

Refractive Index

n20/D 1.469

SMILES

View in Editor

CC(C)(C)OC(=O)N1CCCC(C1)CN

InChI

InChI=1S/C11H22N2O2/c1-11(2,3)15-10(14)13-6-4-5-9(7-12)8-13/h9H,4-8,12H2,1-3H3

InChIKey

WPWXYQIMXTUMJB-UHFFFAOYSA-N

LogP

1.5922

Topological Polar Surface Area

55.56 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

223

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

tert-butyl 3-(aminomethyl)
FT-0630106
3-Aminomethyl-piperidine-1-carboxylic acid tert-butyl ester
3-(Aminomethyl)-1-Boc-piperidine
PB18638
CS-D0643
tert-butyl 3-(aminomethyl)piperidine-1-carboxylate
HMS1704M01
MFCD01317792
AKOS000302909
DTXSID00373387
tert-butyl 3-(aminomethyl)piperidinecarboxylate
STR08085
SY007351
1-Boc-3-(aminomethyl)piperidine, 90%
SY007352
3-aminomethyl-1-n-boc-piperidine
(3R)-1-Boc-3-(aminomethyl)piperidine
tert-butyl 3-(aminomethyl)-1-piperidinecarboxylate
1,1-dimethylethyl 3-(aminomethyl)-1-piperidinecarboxylate
PS-3861
3-(Aminomethyl)-1-piperidinecarboxylic Acid tert-Butyl Ester
PB12777
3-Aminomethylpiperidine-1-carboxylic acid tert-butyl ester
FT-0601665
FT-0650484
Q-200362
3-(Aminomethyl)-1-N-Boc-piperidine
PB14224
AM20080447
BCP30904

MDL Number

MFCD01317792

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2-Methyl-2-propanyl 3-(aminomethyl)-1-piperidinecarboxylate (CAS: 162167-97-7)?

2-Methyl-2-propanyl 3-(aminomethyl)-1-piperidinecarboxylate (CAS: 162167-97-7) is a colorless to slightly yellow crystalline solid with a molecular weight of approximately 226.35 g/mol. It has a solubility in water of about 2 g/L at 20°C. The compound is moderately reactive, particularly susceptible to hydrolysis under basic conditions. It is soluble in common organic solvents such as methanol and acetonitrile.

How is 2-Methyl-2-propanyl 3-(aminomethyl)-1-piperidinecarboxylate (CAS: 162167-97-7) typically synthesized?

2-Methyl-2-propanyl 3-(aminomethyl)-1-piperidinecarboxylate (CAS: 162167-97-7) is typically synthesized through the reaction of 3-(aminomethyl)-1-piperidinecarboxylic acid with 2-methyl-2-propanol. The synthesis usually involves esterification under basic conditions, using sodium hydroxide or potassium hydroxide as catalysts. The reaction yields a mixture that can be purified by recrystallization from an appropriate solvent.

What industries use 2-Methyl-2-proanyl 3-(aminomethyl)-1-piperidinecarboxylate (CAS: 162167-97-7)?

2-Methyl-2-proanyl 3-(aminomethyl)-1-piperidinecarboxylate (CAS: 162167-97-7) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It also finds applications in the polymer industry for the preparation of functionalized polymers and in sensor technology for the development of biosensors and chemosensors.

What precautions should be taken when handling 2-Methyl-2-proanyl 3-(aminomethyl)-1-piperidinecarboxylate (CAS: 162167-97-7)?

When handling 2-Methyl-2-proanyl 3-(aminomethyl)-1-piperidinecarboxylate (CAS: 162167-97-7), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coat. Work should be done in a well-ventilated area or a fume hood to avoid inhalation. Spills should be handled by sweeping or vacuuming, not by sweeping with a broom. Follow standard laboratory safety protocols and consult the Material Safety Data Sheet (MSDS/SDS) for detailed handling instructions.