(1R,3S)-3-{[(tert-butoxy)carbonyl]amino}cyclopentane-1-carboxylic acid

Basic Information

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CAS Number

161660-94-2

Molecular Formula

C11H19NO4

Molecular Weight

229.28 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

96.1 °C

Boiling Point

382.5℃ at 760 mmHg

Flash Point

185.1℃

Refractive Index

1.4490 (estimate)

SMILES

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CC(C)(C)OC(=O)NC1CCC(C1)C(=O)O

InChI

InChI=1S/C11H19NO4/c1-11(2,3)16-10(15)12-8-5-4-7(6-8)9(13)14/h7-8H,4-6H2,1-3H3,(H,12,15)(H,13,14)/t7-,8+/m1/s1

InChIKey

RNJQBGXOSAQQDG-SFYZADRCSA-N

LogP

1.7644000000000002

Topological Polar Surface Area

75.63 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

282

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

cis-3-(Boc-amino)cyclopentanecarboxylic Acid
Cyclopentanecarboxylic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-, (1R,3S)-
cis(1R,3S)-3-((tert-butoxycarbonyl)amino) cyclopentanecarboxylic acid
PD019190
(1R,3S)-3-{[(tert-butoxy)carbonyl]amino}cyclopentane-1-carboxylic acid
CIS-3-(BOC-AMINO)CYCLOPENTANE-1-CARBOXYLIC ACID
(-)-(1s,3r)-n-boc-aminocyclopentane-3-carboxylic acid
(1R,3S)-Boc-3-aminocyclopentane-1 carboxylic acid
DTXSID70936569
Boc-cis-NH(3)cPen-OH
A1-52905
(1R,3S)-3-(tert-butoxycarbonylamino)cyclopentanecarboxylic acid
(1R,3S)-3-[(tert-butoxycarbonyl)amino]cyclopentanecarboxylic acid
DS-14793
(1R,3S)-3-(t-butoxycarbonylamino)cyclopentanecarboxylic acid
(1R,3S)-N-Boc-1-Aminocyclopentane-3-carboxylic acid
(1R,3S)-3-((tert-Butoxycarbonyl)amino)cyclopentanecarboxylic acid
(1R,3S)-3-(BOC-amino)cyclopentanecarboxylic acid
(1S,3R)-(+)-3-(Boc-amino)cyclopentanecarboxylic acid
AKOS016344288
(1R,3S)-3-t-Butoxycarbonylaminocyclopentanecarboxylic acid
MFCD01320858
cis-3-(N-tert-Butoxycarbonylamino)cyclopentanecarboxylic acid
MFCD09992879
cis-3-(tert-Butoxycarbonylamino)cyclopentanecarboxylic acid
MFCD01320857
RNJQBGXOSAQQDG-SFYZADRCSA-N
CS-W004812
BB 0260212
(1R,3S)-3-(Boc-amino)cyclopentane-1-carboxylic acid
EN300-1589930

MDL Number

MFCD01320858

Customs Code

2924299090

FAQ

What are the physical and chemical properties of (1R,3S)-3-{[(tert-butoxy)carbonyl]amino}cyclopentane-1-carboxylic acid (CAS: 161660-94-2)?

This compound is a white crystalline solid with a molecular weight of approximately 268.4 g/mol. It has low solubility in water but is soluble in organic solvents like methanol and acetonitrile. Chemically, it is stable but can react with strong acids to form carboxylic acid derivatives. It is less reactive towards bases and nucleophiles.

How is (1R,3S)-3-{[(tert-butoxy)carbonyl]amino}cyclopentane-1-carboxylic acid (CAS: 161660-94-2) typically synthesized?

It is synthesized via a multi-step process, starting from cyclopentanecarboxylic acid and a protecting group such as BOC (tert-butoxycarbonyl) using standard coupling reactions. The specific synthesis involves protecting the amino group, followed by the introduction of the tert-butoxy carbonyl group, and subsequent deprotection to yield the final product.

What industries use (1R,3S)-3-{[(tert-butoxy)carbonyl]amino}cyclopentane-1-carboxylic acid (CAS: 161660-94-2)?

This compound is primarily used in the pharmaceutical industry for the synthesis of biologically active molecules. It is also applied in the polymer industry for the development of advanced materials and in the sensor industry for specific chemical and biological detection applications.

What precautions should be taken when handling (1R,3S)-3-{[(tert-butoxy)carbonyl]amino}cyclopentane-1-carboxylic acid (CAS: 161660-94-2)?

It should be handled in a well-ventilated area with appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. It should be stored in a fume hood and away from strong acids and bases. In case of a spill, it should be handled according to the Material Safety Data Sheet (MSDS) guidelines, and the area should be cleaned with appropriate solvents. Immediate medical attention should be sought if exposure occurs.