N,N,N',N',N'',N''-Hexamethylphosphorous triamide

Basic Information

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CAS Number

1608-26-0

Molecular Formula

C6H18N3P

Molecular Weight

163.2 g/mol

Chemical Classification

Agricultural Chemicals Pesticides Insecticides

Basic Physical Properties

Melting Point

-44 ºC

Boiling Point

163°C

Refractive Index

n20/D 1.463(lit.)

SMILES

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CN(C)P(N(C)C)N(C)C

InChI

InChI=1S/C6H18N3P/c1-7(2)10(8(3)4)9(5)6/h1-6H3

InChIKey

XVDBWWRIXBMVJV-UHFFFAOYSA-N

LogP

0.8980999999999999

Topological Polar Surface Area

9.72 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

Safety Information

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GHS Hazard Pictograms

H226

H340

H350

Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

H340 May cause genetic defects
Germ cell mutagenicity

H350 May cause cancer
Carcinogenicity

Hazard Class

Class 3 Class 3

Stability

Stable. Highly flammable - note low flash point. Incompatible with oxidizing agents.

Sensitiveness

Moisture Sensitive

Synonyms & References

English

[bis(dimethylamino)phosphanyl]dimethylamine
EINECS 216-534-4
UNII-6072HG2UW4
59758-27-9
A810188
Hexamethylphosphorous triamide
4-04-00-00274 (Beilstein Handbook Reference)
BRN 0906778
Hexamethyl phosphorous triamide
BCP22562
1608-26-0
NSC 102707
NSC102707
J-802222
STR07323
Hexamethyltriamidophosphite
NSC-102707
Trisdimethylaminophosphine
HMPT (VAN)
AI3-19434
AMY39380
trisdimethylaminophosphorus
Tris(dimethylamino)phosphine, 97%
N,N,N',N',N'',N''-hexamethylphosphorous triamide
N-[bis(dimethylamino)phosphino]-N-methylmethanamine
N,N,N',N',N'',N''-HEXAMETHYLPHOSPHINETRIAMINE
tris (dimethylamino)phosphine
BP-13042
phosphorous triamide, N,N,N',N',N'',N''-hexamethyl-
Hexamethyltriaminophosphine
Tris(dimethylamino)phosphine, purum, >=97.0% (GC)

MDL Number

MFCD00008301

Customs Code

29299000

FAQ

What are the physical and chemical properties of N,N,N',N',N'',N''-Hexamethylphosphorous triamide (CAS: 1608-26-0)?

N,N,N',N',N'',N''-Hexamethylphosphorous triamide (HMTA, CAS: 1608-26-0) is a white crystalline solid with a molecular weight of approximately 204.23 g/mol. It is slightly soluble in water but readily soluble in organic solvents like ethanol and acetone. Chemically, it is a stable compound but can react with strong acids to form phosphoric acid derivatives. It has a boiling point of 277°C and a melting point of 120-123°C.

How is N,N,N',N',N'',N''-Hexamethylphosphorous triamide (CAS: 1608-26-0) typically synthesized?

N,N,N',N',N'',N''-Hexamethylphosphorous triamide (HMTA, CAS: 1608-26-0) is usually synthesized via the reaction of phosphorus oxychloride with methylamine followed by a series of methylamine additions. This process requires careful control of temperature and reaction conditions to achieve high yields and selectivity. Catalysts like potassium carbonate or sodium carbonate are often used to improve the reaction efficiency and product purity.

What industries use N,N,N',N',N'',N''-Hexamethylphosphorous triamide (CAS: 1608-26-0)?

N,N,N',N',N'',N''-Hexamethylphosphorous triamide (HMTA, CAS: 1608-26-0) finds applications across various industries. It is widely used in the pharmaceutical sector for the synthesis of certain chemical intermediates, in polymer manufacturing as a crosslinking agent, and in the production of sensors and semiconductors for electronic applications. Its stability and reactivity make it a valuable reagent in these fields.

What precautions should be taken when handling N,N,N',N',N'',N''-Hexamethylphosphorous triamide (CAS: 1608-26-0)?

When handling N,N,N',N',N'',N''-Hexamethylphosphorous triamide (HMTA, CAS: 1608-26-0), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Ensure that work is conducted in a well-ventilated area or a fume hood to minimize exposure to vapors. Spills should be cleaned up using appropriate absorbents and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed guidance on handling and storage.