Compound Q&A
How is N,N,N',N',N'',N''-Hexamethylphosphorous triamide (CAS: 1608-26-0) typically synthesized?
Answer
N,N,N',N',N'',N''-Hexamethylphosphorous triamide (HMTA, CAS: 1608-26-0) is usually synthesized via the reaction of phosphorus oxychloride with methylamine followed by a series of methylamine additions. This process requires careful control of temperature and reaction conditions to achieve high yields and selectivity. Catalysts like potassium carbonate or sodium carbonate are often used to improve the reaction efficiency and product purity.
About
CAS No
1608-26-0
English Name
N,N,N',N',N'',N''-Hexamethylphosphorous triamide
Molecular Formula
C6H18N3P
Molecular Weight
163.2 g/mol
SMILES
CN(C)P(N(C)C)N(C)C
InChIKey
XVDBWWRIXBMVJV-UHFFFAOYSA-N
Last Updated: 2025-09-08 00:42
