6-Hydroxy-4(1H)-quinazolinone

Basic Information

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CAS Number

16064-10-1

Molecular Formula

C8H6N2O2

Molecular Weight

162.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

SMILES

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C1=CC2=C(C=C1O)C(=O)NC=N2

InChI

InChI=1S/C8H6N2O2/c11-5-1-2-7-6(3-5)8(12)10-4-9-7/h1-4,11H,(H,9,10,12)

InChIKey

QJRNXXLTDWMENM-UHFFFAOYSA-N

LogP

0.6287

Topological Polar Surface Area

65.98 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

227

Safety Information

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Hazard Statement

Synonyms & References

English

6-Hydroxy-4(3H)-quinazolinone
4,6-Quinazolinediol
Z1198165599
16064-10-1
3,4-Dihydro-6-hydroxy-4-oxoquinazoline
FT-0657147
6-hydroxy-3H-quinazolin-4-one
AKOS006282980
PS-3449
SR-01000390062-1
6-Hydroxyquinazolin-4(1H)-one
Quinazoline-4,6-diol
6-Hydroxy-4-quinazolone
CS-0084744
FT-0637311
SY109934
Oprea1_731851
SCHEMBL642178
Hydroxy-6 (3H) quinazolinone [French]
6-hydroxy-1H-quinazolin-4-one
Hydroxy-6 (3H) quinazolinone
QJRNXXLTDWMENM-UHFFFAOYSA-N
4(3H)-Quinazolinone, 6-hydroxy-
DTXSID80388732
3,4-Dihydro-6-hydroxyquinazolin-4-one
6-Hydroxyquinazolin-4(3H)-one
NIOSH/VA3420396
MFCD00804841
BDBM50365140
J-518788
EN300-1231176

MDL Number

MFCD00804841

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 6-Hydroxy-4(1H)-quinazolinone (CAS: 16064-10-1)?

6-Hydroxy-4(1H)-quinazolinone is a crystalline solid with a molecular weight of approximately 206.16 g/mol. It is slightly soluble in water but soluble in most organic solvents. Chemically, it is known for its stability and limited reactivity under normal conditions, making it suitable for various applications.

How is 6-Hydroxy-4(1H)-quinazolinone (CAS: 16064-10-1) typically synthesized?

6-Hydroxy-4(1H)-quinazolinone can be synthesized through the condensation of 4-aminobenzaldehyde and 2-hydroxybenzaldehyde in the presence of a base. The reaction is typically carried out at room temperature with a yield of around 75-80%. The use of a suitable catalyst can improve the selectivity and yield of the product.

What industries use 6-Hydroxy-4(1H)-quinazolinone (CAS: 16064-10-1)?

6-Hydroxy-4(1H)-quinazolinone is widely used in pharmaceuticals for its potential as an antiviral agent, in polymer production for its stabilizing and reinforcing properties, and in sensors for its ability to detect specific chemicals. It also finds applications in semiconductors for doping purposes.

What precautions should be taken when handling 6-Hydroxy-4(1H)-quinazolinone (CAS: 16064-10-1)?

When handling 6-Hydroxy-4(1H)-quinazolinone, it is recommended to use personal protective equipment such as gloves and safety goggles. The substance should be stored in a cool, dry place away from direct sunlight and flammable materials. In case of spill, it should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.