5-Indolinecarboxylic acid

Basic Information

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CAS Number

15861-30-0

Molecular Formula

C9H9NO2

Molecular Weight

163.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Boiling Point

369.037 °C at 760 mmHg

Density

1.284

Flash Point

369.037 °C at 760 mmHg

Refractive Index

1.611

SMILES

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C1CNC2=C1C=C(C=C2)C(=O)O

InChI

InChI=1S/C9H9NO2/c11-9(12)7-1-2-8-6(5-7)3-4-10-8/h1-2,5,10H,3-4H2,(H,11,12)

InChIKey

DZTLKUKANGQSRN-UHFFFAOYSA-N

LogP

1.3528

Topological Polar Surface Area

49.33 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

193

Synonyms & References

English

DZTLKUKANGQSRN-UHFFFAOYSA-N
1H-Indole-5-carboxylic acid, 2,3-dihydro-
AKOS001200253
2,3-dihydro-1H-indole-5-carboxylic Acid
A21420
indoline-5-carboxylic acid
FT-0688922
EN300-23678
AC-27801
15861-30-0
1H-INDOLE-5-CARBOXYLIC ACID,2,3-DIHYDRO-,
BS-13605
SB33958
BB 0262347
MFCD07371642
Z164676906
Q-102597
DTXSID00429272
Indoline-5-carboxylic acid, AldrichCPR
CS-W019001
HMS1773A12
SCHEMBL2638095
indoline-5-carboxylicacid
Indoline-5-carboxylic acid
2,3-DIHYDRO-1H-INDOLE-5-CARBOXYLIC ACID
5-carboxylindoline
2,3-Dihydro-1H-indole-5-carboxylic acid methyl ester
Indoline-5-carboxylic acid ,97%
RP22619
ST2407048
1H-Indole-5-carboxylicacid, 2,3-dihydro-

MDL Number

MFCD07371642

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 5-Indolinecarboxylic acid (CAS: 15861-30-0)?

5-Indolinecarboxylic acid is a crystalline solid with a molecular weight of approximately 147.17 g/mol. Its solubility in water is low, around 0.05 g/L at 20°C. Chemically, it is moderately reactive, showing some acidity and reactivity towards nucleophiles. It is often used in organic synthesis due to its carboxylic acid functionality.

How is 5-Indolinecarboxylic acid (CAS: 15861-30-0) typically synthesized?

5-Indolinecarboxylic acid is commonly synthesized via the condensation of indoline with carbon dioxide. The reaction typically requires a suitable catalyst such as a metal oxide or an acid. High selectivity and good yield can be achieved under optimized conditions, usually involving reflux or heating under pressure. Detailed procedures are described in various organic synthesis literature.

What industries use 5-Indolinecarboxylic acid (CAS: 15861-30-0)?

5-Indolinecarboxylic acid finds applications in multiple industries. It is used in pharmaceuticals for the synthesis of certain drugs, in polymers for the modification of polymer properties, in sensors for detecting specific chemical species, and in semiconductors for the production of organic electronic materials. Its reactivity and functional groups make it versatile for various applications.

What precautions should be taken when handling 5-Indolinecarboxylic acid (CAS: 15861-30-0)?

When handling 5-Indolinecarboxylic acid, it is important to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and lab coats. Work should be conducted in a well-ventilated area or a fume hood to prevent inhalation of dust. Spills should be cleaned up promptly using appropriate absorbents. Always consult the Safety Data Sheet (SDS) for detailed handling and emergency procedures.