2,3-Diethylpyrazine

Basic Information

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CAS Number

15707-24-1

Molecular Formula

C8H12N2

Molecular Weight

136.2 g/mol

Basic Physical Properties

Boiling Point

71°C/12mmHg

Refractive Index

n20/D 1.5(lit.)

SMILES

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CCc1c(nccn1)CC

InChI

InChI=1S/C8H12N2/c1-3-7-8(4-2)10-6-5-9-7/h5-6H,3-4H2,1-2H3

InChIKey

GZXXANJCCWGCSV-UHFFFAOYSA-N

LogP

1.6014

Topological Polar Surface Area

25.78 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

81.3

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H318 Causes serious eye damage
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

2,3-Diethylpyrazine
2.3-Diethylpyrazine
2,3,6-TRIMETHOXY-BENZALDEHYDE
2,3-Diethyl-pyrazin
2,3-Diethyl-pyrazine
EINECS 239-800-1
FEMA No. 3136
Pyrazine,2,3-diethyl
tetramethyl pyrazine

MDL Number

MFCD00006151

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 2,3-Diethylpyrazine (CAS: 15707-24-1)?

2,3-Diethylpyrazine (CAS: 15707-24-1) is a colorless liquid with a strong, pleasant aroma. It has a molecular weight of approximately 112.14 g/mol. The compound is slightly soluble in water but miscible with common organic solvents like ethanol and acetone. It is stable under normal conditions but can react with strong oxidizers. Its vapor pressure is relatively low, and it has a distinct odor at low concentrations.

How is 2,3-Diethylpyrazine (CAS: 15707-24-1) typically synthesized?

2,3-Diethylpyrazine is synthesized via the condensation of ethyl cyanoacetate and ethyl isocyanide. The reaction proceeds under mild conditions with a yield of about 75%. Commonly, azeotropic distillation is used to purify the product. Catalysts such as p-toluenesulfonic acid can enhance the selectivity and yield of the product.

What industries use 2,3-Diethylpyrazine (CAS: 15707-24-1)?

2,3-Diethylpyrazine (CAS: 15707-24-1) is widely used in the food and flavor industry as a flavor enhancer due to its pleasant aroma. It also finds applications in the perfume industry as a fragrance component. Additionally, it is used in the pharmaceutical industry as a flavoring agent for medicines and in the polymer industry for plastic fragrance additives.

What precautions should be taken when handling 2,3-Diethylpyrazine (CAS: 15707-24-1)?

When handling 2,3-Diethylpyrazine (CAS: 15707-24-1), it is essential to wear appropriate personal protective equipment (PPE), including safety goggles, gloves, and a lab coat. Work in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up using a suitable absorbent material, and the area should be flushed with water. Refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.