4-Bromonicotinic acid

Basic Information

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CAS Number

15366-62-8

Molecular Formula

C6H4BrNO2

Molecular Weight

202.01 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

118-134 °C

Boiling Point

334.5°Cat760mmHg

Density

1.813

Flash Point

156.1°C

Refractive Index

1.616

SMILES

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C1=CN=CC(=C1Br)C(=O)O

InChI

InChI=1S/C6H4BrNO2/c7-5-1-2-8-3-4(5)6(9)10/h1-3H,(H,9,10)

InChIKey

CZLOEKRJQIAKFI-UHFFFAOYSA-N

LogP

1.5423

Topological Polar Surface Area

50.19 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

140

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Hazard Class

Class IRRITANT Class IRRITANT

Class KEEP COLD Class KEEP COLD

Class STORED UNDER ARGON Class STORED UNDER ARGON

Synonyms & References

English

CS-W007332
W-205747
3-PYRIDINECARBOXYLIC ACID, 4-BROMO-
CZLOEKRJQIAKFI-UHFFFAOYSA-N
3- acid - 4- bromopyridine
SCHEMBL933359
4-Bromo-nicotinic acid
4-Bromopyridine-3-carboxylic acid, 95%
4-bromopyridine-3-carboxylic Acid
AC-1732
EN300-96228
AKOS005198946
4-Bromonicotinic acid
4-BROMO-NICOTINICACID
4-bromonicotinicacid
AM20050833
SY021899
15366-62-8
4-Bromonicotinic acid, AldrichCPR
DTXSID00376570
FT-0649640
MFCD04114236
4-Bromo-3-pyridine carboxlic acid
4-bromo-nicotinicacidhydrochloride
AB18009
BCP05403
DS-0438
4-Bromopyridine-3-carboxylic acid
4-Bromo-3-pyridinecarboxylic acid
3-acid-4-bromopyridine
3-Pyridinecarboxylicacid, 4-broMo-

MDL Number

MFCD04114236

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 4-Bromonicotinic acid (CAS: 15366-62-8)?

4-Bromonicotinic acid is a crystalline solid with a molecular weight of 215.02 g/mol. It has a solubility of about 1.8 g/L in water at 20°C. Chemically, it is less reactive than nicotinic acid but can undergo typical carboxylic acid reactions such as esterification and neutralization.

How is 4-Bromonicotinic acid (CAS: 15366-62-8) typically synthesized?

4-Bromonicotinic acid is usually synthesized by bromination of nicotinic acid. This involves treating nicotinic acid with bromine in the presence of a solvent like acetone or acetic acid. The reaction is selective and provides a yield of about 85%.

What industries use 4-Bromonicotinic acid (CAS: 15366-62-8)?

4-Bromonicotinic acid finds applications in the pharmaceutical industry for the synthesis of certain drugs. It is also used in the chemical industry for making dyes, pigments, and as an intermediate in some polymer synthesis processes.

What precautions should be taken when handling 4-Bromonicotinic acid (CAS: 15366-62-8)?

When handling 4-Bromonicotinic acid, wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Store it in a cool, dry place away from direct sunlight. In case of a spill, use appropriate safety equipment to clean up and consult the Material Safety Data Sheet (MSDS) for detailed instructions.