4-Bromonicotinic acid(CAS: 15366-62-8)

4-Bromonicotinic acid is a crystalline solid with a molecular weight of 215.02 g/mol. It has a solubility of about 1.8 g/L in water at 20°C. Chemically, it is less reactive than nicotinic acid but can undergo typical carboxylic acid reactions such as esterification and neutralization.

4-Bromonicotinic acid is usually synthesized by bromination of nicotinic acid. This involves treating nicotinic acid with bromine in the presence of a solvent like acetone or acetic acid. The reaction is selective and provides a yield of about 85%.

4-Bromonicotinic acid finds applications in the pharmaceutical industry for the synthesis of certain drugs. It is also used in the chemical industry for making dyes, pigments, and as an intermediate in some polymer synthesis processes.

When handling 4-Bromonicotinic acid, wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Store it in a cool, dry place away from direct sunlight. In case of a spill, use appropriate safety equipment to clean up and consult the Material Safety Data Sheet (MSDS) for detailed instructions.