(2R)-2-amino-3-(1H-indol-3-yl)propanoic acid

Basic Information

View in Editor

CAS Number

153-94-6

Molecular Formula

C11H12N2O2

Molecular Weight

204.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

282-285 °C (dec.)

Boiling Point

447.9°C at 760 mmHg

Water Solubility

11 g/L (20 ºC)

Flash Point

195.4°C

Refractive Index

31 ° (C=1, H2O)

Specific Rotation

31.5 º (c=1, H2O 24 ºC)

SMILES

View in Editor

N[C@H](Cc1c[nH]c2ccccc12)C(=O)O

InChI

InChI=1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m1/s1

InChIKey

QIVBCDIJIAJPQS-SECBINFHSA-N

LogP

1.1223000000000003

Topological Polar Surface Area

79.11 Å²

Hydrogen Bond Donor/Acceptor

4 / 4

Complexity

245

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Stability

Stable. Incompatible with oxidizing agents.

Synonyms & References

English

D-Tryptophan
(R)-2-Amino-3-(3-indolyl)propionic acid
H-D-Trp-OH
D(+)-Tryptophan
D-Trytophan
(R)-(+)-2-AMINO-3-(3-INDOLYL)PROPIONIC ACID
CBZ-D-TRP BR
D-(+)-Tryptophan
D-Trp
Tryptophan
TRYPTOPHAN, D-(RG)
(2R)-2-amino-3-(1H-indol-3-yl)propanoic acid
?-(+)-Tryptophan
?-2-AMino-3-(3-indolyl)propionic acid
D-2-AMino-3- indolylpropanoic acid
D-α-Amino-3-indolepropionic acid
D-β-3-Indolyl alanine
D-alpha-Amino-3-indolepropionic acid
3,3'-Indolyl-2-alanine
(+)-Tryptophan
LTR
TRP-01
D-Trp-OH
(S)-alph
NSC 97942
H-D-TYP-OH
d-tryptopha
WV
(R)-Tryptophan
D-TRYPTOPHANE
D-Trytophane

MDL Number

MFCD00005647

Customs Code

29339990

FAQ

What is (2R)-2-amino-3-(1H-indol-3-yl)propanoic acid (CAS: 153-94-6)?

(2R)-2-amino-3-(1H-indol-3-yl)propanoic acid, with CAS number 153-94-6, is a chiral organic compound that contains an indole ring and an amino acid backbone. It is commonly used in pharmaceutical research due to its potential biological activity. The compound has a molecular formula of C12H13N2O2 and is typically a white to pale yellow solid with a melting point around 220-222°C.

What are the main uses of (2R)-2-amino-3-(1H-indol-3-yl)propanoic acid (CAS: 153-94-6)?

(2R)-2-amino-3-(1H-indol-3-yl)propanoic acid (CAS: 153-94-6) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It has shown potential in medicinal chemistry for applications related to central nervous system disorders. Researchers also use it in studies involving receptor binding and molecular interactions due to its structural similarity to neurotransmitters.

Is (2R)-2-amino-3-(1H-indol-3-yl)propanoic acid (CAS: 153-94-6) safe?

(2R)-2-amino-3-(1H-indol-3-yl)propanoic acid (CAS: 153-94-6) is generally considered safe when handled properly in controlled laboratory environments. However, as a chemical compound, it may have toxic effects if ingested or inhaled in large quantities. Safety precautions include wearing protective gear and ensuring proper ventilation. It is important to follow established safety standards during its use and disposal.

How should (2R)-2-amino-3-(1H-indol-3-yl)propanoic acid (CAS: 153-94-6) be stored?

(2R)-2-amino-3-(1H-indol-3-yl)propanoic acid (CAS: 153-94-6) should be stored in a cool, dry, and dark place to maintain its stability. It is best kept in a sealed container at a temperature below 25°C and away from moisture and light. Proper storage helps prevent degradation and ensures the compound remains chemically active for research or industrial purposes.