5-Hydroxynicotinonitrile

Basic Information

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CAS Number

152803-24-2

Molecular Formula

C6H4N2O

Molecular Weight

120.11 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

213-217℃

Boiling Point

394.737 °C at 760 mmHg

Density

1.332

Water Solubility

Slightly soluble in water.

Flash Point

192.53 °C

SMILES

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C1=C(C=NC=C1O)C#N

InChI

InChI=1S/C6H4N2O/c7-2-5-1-6(9)4-8-3-5/h1,3-4,9H

InChIKey

KAXIYYPIORYZLB-UHFFFAOYSA-N

LogP

0.65888

Complexity

137

Safety Information

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Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

InChI=1/C6H4N2O/c7-2-5-1-6(9)4-8-3-5/h1,3-4,9H
3-Pyridinecarbonitrile,5-hydroxy-(9CI)
AKOS005199147
FT-0650033
5-Hydroxy-nicotinonitrile
AC-4595
3-cyano-5-hydroxypyridine
SCHEMBL875703
5-hydroxypyridine-3-carbonitrile
RB1124
KAXIYYPIORYZLB-UHFFFAOYSA-N
SY047292
152803-24-2
AM62681
MFCD11044307
J-512359
5-hydroxynicotinonitrile
DTXSID70571757
CS-W016581
3-Pyridinecarbonitrile, 5-hydroxy-
DS-10775
KAXIYYPIORYZLB-UHFFFAOYSA-
3-Cyano-5-hydroxypyridine, 97%
EN300-127588
MB09110
5-HYDROXY-3-PYRIDINECARBONITRILE
Z1198307115
3-PYRIDINECARBONITRILE,5-HYDROXY
3-Cyano-5-hydroxypyridine
5-Hydroxynicotinonitrile
5-isocyano-pyridin-3-ol

MDL Number

MFCD11044307

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 5-Hydroxynicotinonitrile (CAS: 152803-24-2)?

5-Hydroxynicotinonitrile (CAS: 152803-24-2) is a white crystalline solid with a molecular weight of approximately 145.12 g/mol. It is slightly soluble in water but more soluble in organic solvents such as ethanol and acetone. The compound is known for its moderate reactivity, particularly in nucleophilic substitution reactions.

How is 5-Hydroxynicotinonitrile (CAS: 152803-24-2) typically synthesized?

5-Hydroxynicotinonitrile is typically synthesized via the hydroxylammonium nitrite method. A common procedure involves the reaction of hydroxylamine hydrochloride with nicotinonitrile in the presence of a catalyst such as sodium hydroxide. The yield can be up to 85%, and the method is known for its high selectivity.

What industries use 5-Hydroxynicotinonitrile (CAS: 152803-24-2)?

5-Hydroxynicotinonitrile (CAS: 152803-24-2) is used in various industries, including pharmaceuticals for intermediate production, sensors for detecting specific chemical species, and in the synthesis of certain polymers. Its applications are expanding due to its unique chemical properties.

What precautions should be taken when handling 5-Hydroxynicotinonitrile (CAS: 152803-24-2)?

When handling 5-Hydroxynicotinonitrile (CAS: 152803-24-2), it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be handled with caution, and appropriate spill cleanup procedures should be followed. Always refer to the Safety Data Sheet (SDS) for detailed instructions.