(3R,5S)-5-{[Bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-3-pyrrolidinol | CAS No. 151953-64-9

(3R,5S)-5-{[Bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-3-pyrrolidinol

Basic Information

CAS Number

151953-64-9

Molecular Formula

C26H29NO4

Molecular Weight

419.52 g/mol

AD

Basic Physical Properties

O(C(c1ccccc1)(c2ccc(OC)cc2)c3ccc(OC)cc3)C[C@H]4NC[C@H](O)C4

InChI

InChI=1S/C26H29NO4/c1-29-24-12-8-20(9-13-24)26(19-6-4-3-5-7-19,21-10-14-25(30-2)15-11-21)31-18-22-16-23(28)17-27-22/h3-15,22-23,27-28H,16-18H2,1-2H3/t22-,23+/m0/s1

InChIKey

CJFYBUJBXCVKLN-XZOQPEGZSA-N

LogP

3.735100000000002

Topological Polar Surface Area

59.95 Ų

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

498

Synonyms & References

English

  • 3-Pyrrolidinol, 5-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-,(3R,5S)-
  • (3R,5S)-5-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}pyrrolidin-3-ol
  • (3R,5S)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]pyrrolidin-3-ol
  • (3r,5s)-5-{[bis(4-methoxyphenyl)(phenyl)methoxy]methylpyrrolidin-3-ol
  • (3R,5S)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)pyrrolidin-3-ol
  • (3r,5s)-5-{[bis(4-methoxyphenyl)(phenyl) methoxy]methyl}pyrrolidine-3-ol

MDL Number

MFCD29918292

FAQ

What are the physical and chemical properties of (3R,5S)-5-{[Bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-3-pyrrolidinol (CAS: 151953-64-9)?

(3R,5S)-5-{[Bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-3-pyrrolidinol is a white crystalline solid with a molecular weight of approximately 532.4 g/mol. It has low solubility in water but is soluble in organic solvents such as ethanol and acetone. The compound is known for its reactivity, particularly in forming esters and amides. Its stability is relatively high under normal conditions but may degrade under harsh acidic or basic conditions.

How is (3R,5S)-5-{[Bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-3-pyrrolidinol (CAS: 151953-64-9) typically synthesized?

(3R,5S)-5-{[Bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-3-pyrrolidinol is typically synthesized via a multi-step process involving the condensation of pyrrolidine with a benzylated derivative. The synthesis involves the use of a mild base and proceeds with good selectivity, yielding up to 80% purity. The exact methodology can vary depending on the availability of starting materials and desired product purity.

What industries use (3R,5S)-5-{[Bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-3-pyrrolidinol (CAS: 151953-64-9)?

(3R,5S)-5-{[Bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-3-pyrrolidinol is used in various industries, particularly in the pharmaceutical sector for its potential as an intermediate in drug synthesis. It also finds applications in the polymer industry as a functional monomer, and in the development of sensors due to its reactivity and specific chemical properties.

What precautions should be taken when handling (3R,5S)-5-{[Bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-3-pyrrolidinol (CAS: 151953-64-9)?

When handling (3R,5S)-5-{[Bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-3-pyrrolidinol, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The material should be handled in a well-ventilated area or a fume hood. Spills should be carefully managed, and the product should be stored in a cool, dry place away from incompatible materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.

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