N,N-Bis(2-hydroxyethyl)glycine

Basic Information

View in Editor

CAS Number

150-25-4

Molecular Formula

C6H13NO4

Molecular Weight

163.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Physical Properties

Melting Point

190-192 ºC

Boiling Point

388.5℃ at 760 mmHg

Flash Point

188.8℃

Solubility

H2O: 1 M at 20 °C, clear, colorless

Refractive Index

1.526

SMILES

View in Editor

C(CO)N(CCO)CC(=O)O

InChI

InChI=1S/C6H13NO4/c8-3-1-7(2-4-9)5-6(10)11/h8-9H,1-5H2,(H,10,11)

InChIKey

FSVCELGFZIQNCK-UHFFFAOYSA-N

LogP

-1.6423999999999987

pKa

8.3(at 25℃)

Topological Polar Surface Area

81.0 Å²

Hydrogen Bond Donor/Acceptor

3 / 5

Complexity

111

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

moisture-sensitive

Synonyms & References

English

N,N-(2-Hydroxyethyl)glycine
Diethylolglycine
BICINE, BioUltra, >=99.5% (T)
AB00443773-03
s6276
Bicine (cell culture suitable)
EINECS 205-755-1
UNII-1J484QFI1O
GLYCINE, N,N-DIHYDROXYETHYL-
Glycine, N,N-bis(2-hydroxyethyl)-
NS00003493
di(hydroxyethyl)glycine
2-[bis(2-hydroxyethyl)amino]acetic acid
A809025
n,n-bis-(2-hydroxyethyl)-glycine
1J484QFI1O
Fe-3-Specific
B0484
HY-D0868
Diethanol glycine
[Bis(2-hydroxyethyl)amino]acetic acid #
N,N-Bis(beta-hydroxyethyl)glycine
MFCD00004295
Glycine,N-dihydroxyethyl-
SCHEMBL34161
N,N-Bis(2-hydroxyethyl)aminoacetic acid
NSC7512
Z336127920
N,N-Bis(hydroxyethyl)glycine
N,N-Di(2-hydroxyethyl)glycine
N,N-Dihydroxyethyl glycine

MDL Number

MFCD00004295

Customs Code

29225000

FAQ

What is N,N-Bis(2-hydroxyethyl)glycine (CAS: 150-25-4)?

N,N-Bis(2-hydroxyethyl)glycine, also known as Bicine, is a zwitterionic amino acid derivative with the chemical formula C6H13NO4. It functions as a buffering agent, exhibits high water solubility, and is characterized by its ability to stabilize pH in aqueous solutions. Commonly used in biochemical and pharmaceutical applications, it has a pKa value of approximately 9.8, making it effective in physiological pH ranges.

What are the main uses of N,N-Bis(2-hydroxyethyl)glycine (CAS: 150-25-4)?

N,N-Bis(2-hydroxyethyl)glycine is widely utilized as a buffer in pharmaceuticals, biochemistry, and industrial processes. It aids in stabilizing proteins and enzymes, acts as a chelating agent, and is employed in the production of food additives for pH control. Additionally, it finds applications in research for chromatography and as a component in cosmetic formulations due to its mild properties and compatibility with various substances.

Is N,N-Bis(2-hydroxyethyl)glycine (CAS: 150-25-4) safe?

N,N-Bis(2-hydroxyethyl)glycine is generally considered safe when handled according to standard safety protocols. It has low toxicity and is recognized as GRAS (Generally Recognized as Safe) by the FDA for food use. However, precautions such as wearing gloves, goggles, and ensuring proper ventilation are recommended during handling. It complies with safety standards for industrial and laboratory applications, with minimal risk of harm under controlled conditions.

How should N,N-Bis(2-hydroxyethyl)glycine (CAS: 150-25-4) be stored?

N,N-Bis(2-hydroxyethyl)glycine should be stored in a cool, dry, and dark location to maintain stability. It is best kept in airtight containers to prevent moisture absorption and degradation. Storage at temperatures below 25°C is recommended, and exposure to light or air should be minimized. Ensure it is kept away from incompatible materials to preserve its chemical integrity and safety.