N,N-Bis(2-hydroxyethyl)glycine(CAS: 150-25-4)

N,N-Bis(2-hydroxyethyl)glycine, also known as Bicine, is a zwitterionic amino acid derivative with the chemical formula C6H13NO4. It functions as a buffering agent, exhibits high water solubility, and is characterized by its ability to stabilize pH in aqueous solutions. Commonly used in biochemical and pharmaceutical applications, it has a pKa value of approximately 9.8, making it effective in physiological pH ranges.

N,N-Bis(2-hydroxyethyl)glycine is widely utilized as a buffer in pharmaceuticals, biochemistry, and industrial processes. It aids in stabilizing proteins and enzymes, acts as a chelating agent, and is employed in the production of food additives for pH control. Additionally, it finds applications in research for chromatography and as a component in cosmetic formulations due to its mild properties and compatibility with various substances.

N,N-Bis(2-hydroxyethyl)glycine is generally considered safe when handled according to standard safety protocols. It has low toxicity and is recognized as GRAS (Generally Recognized as Safe) by the FDA for food use. However, precautions such as wearing gloves, goggles, and ensuring proper ventilation are recommended during handling. It complies with safety standards for industrial and laboratory applications, with minimal risk of harm under controlled conditions.

N,N-Bis(2-hydroxyethyl)glycine should be stored in a cool, dry, and dark location to maintain stability. It is best kept in airtight containers to prevent moisture absorption and degradation. Storage at temperatures below 25°C is recommended, and exposure to light or air should be minimized. Ensure it is kept away from incompatible materials to preserve its chemical integrity and safety.