(11beta,16alpha)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl palmitate | CAS No. 14899-36-6
(11beta,16alpha)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl palmitate
Basic Information
CAS Number
14899-36-6
Molecular Formula
C38H59FO6
Molecular Weight
630.88 g/mol
AD
Chemical Classification
Basic Physical Properties
Melting Point
60-65 ºC
Synonyms & References
English
- s5184
- dexamethasone palmitate
- BRN 6031847
- CS-0102469
- UNII-601XWN7060
- Q27263139
- 9-FLUORO-11,17-DIHYDROXY-16-METHYL-21-((1- OXOHEXADECYL)OXY)PREGNA-1,4-DIENE-3,20-DIONE (11.BETA.,16.ALPHA.)-
- Dexamethasone 21-palmitate
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-((1-oxohexadecyl)oxy)-, (11beta,16alpha)-
- NCGC00522021-01
- Palmitic acid, 21-ester with 9-fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione
- NOVA-63035
- CHEBI:31471
- 9-Fluoro-11,17-dihydroxy-16-methyl-21-((1-oxohexadecyl)oxy)pregna-1,4-diene-3,20-dione (11beta,16alpha)-
- AKOS040741625
- HY-128922
- DTXSID8022903
- Limethason
- NOVA63035
- DEXAMETHASONE PALMITATE [WHO-DD]
- Dexamethasone palmitate [JAN]
- D01615
- 601XWN7060
- (11beta,16alpha)-9-fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl hexadecanoate
- MS-30856
- 14899-36-6
- 2-((8S,9R,10S,11S,13S,14S,16R,17R)-9-Fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl palmitate
- Dexamethasone palmitate (JAN)
- Limethason (TN)
- SCHEMBL93887
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11-beta,17,21-trihydroxy-16-alpha-methyl-, 21-palmitate
MDL Number
MFCD01698988
FAQ
What are the physical and chemical properties of (11beta,16alpha)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl palmitate (CAS: 14899-36-6)?
This compound is a steroidal derivative with a molecular weight of approximately 616 g/mol. It is sparingly soluble in water but freely soluble in organic solvents like methanol and ethanol. Chemically, it is stable under normal conditions but can exhibit reactivity towards strong bases and acids. Its crystalline form has a melting point around 190°C.
How is (11beta,16alpha)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl palmitate (CAS: 14899-36-6) typically synthesized?
This compound is typically synthesized via a multi-step process involving the modification of progesterone with fluorination, hydroxylation, and esterification reactions. The synthesis often uses reagents like PTFE and catalytic systems such as palladium-based catalysts to achieve high selectivity and yield.
What industries use (11beta,16alpha)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl palmitate (CAS: 14899-36-6)?
This compound is primarily used in the pharmaceutical industry for research purposes due to its specific structural features. It may also have applications in the production of certain topical formulations. However, its exact use cases are limited given its specialized nature.
What precautions should be taken when handling (11beta,16alpha)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl palmitate (CAS: 14899-36-6)?
Handling this compound should be done in a well-ventilated area or fume hood due to its reactivity. Personal protective equipment (PPE) including gloves and goggles should be worn. In case of spill, immediately clean up with appropriate absorbent materials and follow standard safety protocols. Always refer to the Safety Data Sheet (SDS) for detailed information.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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