Compound Q&A

How is (11beta,16alpha)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl palmitate (CAS: 14899-36-6) typically synthesized?

Answer

(11beta,16alpha)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl palmitate
This compound is typically synthesized via a multi-step process involving the modification of progesterone with fluorination, hydroxylation, and esterification reactions. The synthesis often uses reagents like PTFE and catalytic systems such as palladium-based catalysts to achieve high selectivity and yield.

About

CAS No 14899-36-6
English Name (11beta,16alpha)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl palmitate
Molecular Formula C38H59FO6
Molecular Weight 630.88 g/mol
SMILES CCCCCCCCCCCCCCCC(=O)OCC(=O)C1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)F)O)C)C)O
InChIKey WDPYZTKOEFDTCU-WDJQFAPHSA-N
Last Updated: 2025-10-01 21:42

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