Rifamycin sodium

Basic Information

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CAS Number

14897-39-3

Molecular Formula

C37H47NNaO12

Molecular Weight

720.76 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

152-163°C

Water Solubility

Soluble in water, alcohol and dimethyl sulfoxide.

Solubility

ethanol: soluble50mg/mL

SMILES

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CO[C@H]1/C=C/O[C@@]2(C)Oc3c(C2=O)c2c(O)cc(c(c2c(c3C)O)O)/N=C(/C(=C\C=C\[C@@H]([C@@H]([C@H]([C@H]([C@H]([C@@H]([C@@H]1C)OC(=O)C)C)O)C)O)C)/C)\O.[Na]

InChI

InChI=1S/C37H47NO12.Na/c1-16-11-10-12-17(2)36(46)38-23-15-24(40)26-27(32(23)44)31(43)21(6)34-28(26)35(45)37(8,50-34)48-14-13-25(47-9)18(3)33(49-22(7)39)20(5)30(42)19(4)29(16)41;/h10-16,18-20,25,29-30,33,40-44H,1-9H3,(H,38,46);/b11-10+,14-13+,17-12-;/t16-,18+,19+,20+,25-,29-,30+,33+,37-;/m0./s1

InChIKey

URCDBMLCEGDNOK-NLYBMVFSSA-N

LogP

5.022820000000006

Topological Polar Surface Area

204.79999999999998 Å²

Hydrogen Bond Donor/Acceptor

6 / 13

Complexity

1340

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Rifamycin sodium salt
RIFAMPICIN SV SODIUM
RIFAMYCIN SV-SODIUM
RIFAMYCIN SV SODIUM SALT HEXAHYDRATE
Rifamycin SV Monosodium
RIFAMYCIN,MONOSODIUMSALT
Rifamycin SV hexahydrate sodium salt
RIFAMYCIN S SODIUM SALT
Rifamycin SV monosodium salt
Rifamycin SV Sodium
5,6,9,17,19,21-Hexahydroxy-23-Methoxy-2,4,12,16,18,20,22-heptaMethyl
monosodium rifamycin SV
Rifamycin sodium
Rifamycin SV sodium salt
2,7-(Epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,11(2H)-dione,5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-,21-acetate, sodium salt (8CI)
Rifamycin, monosodium salt (9CI)
2,7-(Epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan, rifamycin deriv.
CB 01-11
NSC 146718
Tuborin
Rifamycin SV s
RifaMycin, sodiuM salt (1:1)
RifamycinSV sodium salt
Rifamycin SV sodium, >=900 IU/mg
Sodium rifomycin SV
Rifamycin, monosodium salt
32086GS35Z
DSSTox_CID_20208
DSSTox_RID_79452
DSSTox_GSID_40208
Rifamycin sodium [USAN]

MDL Number

MFCD00056847

FAQ

What is Rifamycin sodium (CAS: 14897-39-3)?

Rifamycin sodium is an antibiotic compound used primarily in the treatment of bacterial infections. It belongs to the rifamycin class of drugs and has the chemical formula C25H34N4O11. This compound is known for its broad-spectrum antimicrobial activity, particularly against mycobacteria, and is typically used in pharmaceutical formulations for its effectiveness in combating tuberculosis and other serious infections.

What are the main uses of Rifamycin sodium (CAS: 14897-39-3)?

Rifamycin sodium is mainly used in pharmaceuticals to treat tuberculosis and other bacterial infections. It is also utilized in research for studying antimicrobial properties and in the development of new antibiotics. Its broad-spectrum activity makes it valuable in both clinical and industrial applications, especially in the formulation of combination therapies for resistant bacterial strains.

Is Rifamycin sodium (CAS: 14897-39-3) safe?

Rifamycin sodium is generally safe when used as directed, but it may cause side effects such as gastrointestinal discomfort, liver toxicity, and allergic reactions. Proper handling and protective measures, including gloves and eye protection, are recommended during its use. Safety standards are in place to ensure its appropriate use in medical and research settings, and it is classified as a prescription drug requiring professional supervision.

How should Rifamycin sodium (CAS: 14897-39-3) be stored?

Rifamycin sodium should be stored in a cool, dry, and dark place, away from moisture and light. It is typically kept at a temperature range of 15-25°C. The compound should be placed in airtight containers to maintain its stability and prevent degradation. Proper storage conditions are essential to ensure its potency and safety for use.