1-Methoxy-2-propanyl propionate

Basic Information

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CAS Number

148462-57-1

Molecular Formula

C7H14O3

Molecular Weight

146.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

Boiling Point

178 ºC

SMILES

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CCC(=O)OC(C)COC

InChI

InChI=1S/C7H14O3/c1-4-7(8)10-6(2)5-9-3/h6H,4-5H2,1-3H3

InChIKey

DOVZUKKPYKRVIK-UHFFFAOYSA-N

LogP

0.9744999999999999

Topological Polar Surface Area

35.53 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

101

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

MFCD03703426
?Propylene glycol methyl ether propionate
1-methoxypropan-2-yl Propanoate
1-METHOXY-2-PROPYL PROPANOATE
DTXSID50888996
AKOS006277002
148462-57-1
Propylene glycol methyl ether propionate
2-Propanol, 1-methoxy-, propanoate
1-methoxypropan-2-yl propionate
2-Propanol, 1-methoxy-, 2-propanoate
SCHEMBL143195
DOVZUKKPYKRVIK-UHFFFAOYSA-N
Propylene glycol monomethyl ether propionate
1,2,2,6,6-PENTAMETHYLPIPERIDINE D-TARTRATE
PROPYLENE GLYCOL METHYL ETHER PROPIONATE
PEMPIDINE TARTRATE
PIRILENE
PMP
1,2,2,6,6-pentamethylpiperidinetartrate
1,2,2,6,6-pentamethyl-piperidintartrate(1:1)
pempidinatartrato
pempidinebitartrate
1-Methoxy-2-propanol propanoate
2-methoxy-1-methylethyl propionate
2-Propanol,1-methoxy-,2-propanoate
propylene glycol monomethyl ether propionate
1-methoxy-2-propyl propanoate
1-Methoxy-2-propanyl propionate
Propylene glycol methyl ether propiote
PROPYLENE GLYCOL MONOMETHYL ETHER PROPIONATE(PMP)

MDL Number

MFCD03703426

Customs Code

2915390090

FAQ

What are the physical and chemical properties of 1-Methoxy-2-propanyl propionate (CAS: 148462-57-1)?

1-Methoxy-2-propanyl propionate is a colorless to slightly yellowish liquid with a molecular weight of approximately 132.18 g/mol. It has a moderate solubility in water and is miscible with common organic solvents. This compound is known to be moderately reactive, particularly in the presence of bases or under acidic conditions. It has a pKa of around 14, indicating basic behavior. It is crystalline at low temperatures and exhibits good thermal stability up to 100°C.

How is 1-Methoxy-2-propanyl propionate (CAS: 148462-57-1) typically synthesized?

1-Methoxy-2-propanyl propionate is typically synthesized through a Grignard reaction followed by esterification. Specifically, 2-propanol is reacted with a Grignard reagent derived from methoxy magnesium chloride, and the product is then treated with acetic anhydride to form the ester. This method provides good yield and selectivity, although the use of Grignard reagents requires strict handling procedures to prevent hazardous side reactions.

What industries use 1-Methoxy-2-proplyl propionate (CAS: 148462-57-1)?

1-Methoxy-2-propan-2-yl propionate is used in the pharmaceuticals industry as an intermediate in the synthesis of certain drugs. It is also utilized in the polymer industry as a monomer and in the development of functional polymers. Additionally, it has applications in the production of sensors and semiconductors, where its chemical properties make it suitable for specific functional groups and reactions.

What precautions should be taken when handling 1-Methoxy-2-propanyl propionate (CAS: 148462-57-1)?

When handling 1-Methoxy-2-propan-2-yl propionate, it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and lab coat. The compound should be used in a well-ventilated area or under a fume hood due to its reactivity. Spills should be cleaned up carefully, and the material safety data sheet (MSDS) should be consulted for specific cleanup procedures. It is also crucial to store the compound in a cool, dry place, away from strong acids, bases, and oxidizers to prevent degradation and hazardous reactions.